disorganized pancreatic islets Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description derangement of the normal pattern of the hormone-producing cells within an islet; normally, the beta cells occupy the central portion of the islet and are surrounded by a corona of alpha and delta cells (Mammalian Phenotype Ontology, MP_0009254)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009254
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Genes

14 gene mutations causing the disorganized pancreatic islets phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CD38 CD38 molecule
EGFR epidermal growth factor receptor
ERO1LB ERO1-like beta (S. cerevisiae)
GLIS3 GLIS family zinc finger 3
HHIP hedgehog interacting protein
INS insulin
INVS inversin
LEP leptin
MIR375 microRNA 375
NKX2-2 NK2 homeobox 2
ONECUT1 one cut homeobox 1
PAX6 paired box 6
PDX1 pancreatic and duodenal homeobox 1
VIPR1 vasoactive intestinal peptide receptor 1