discoidal high-density lipoprotein particle Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A newly formed high-density lipoprotein particle; consists of a phospholipid bilayer surrounded by two or more APOA1 molecules. The discoidal HDL particle is formed when lipid-free or lipid-poor APOA1 acquires phospholipids and unesterified cholesterol from either cell membranes or triglyceride-rich lipoproteins (undergoing lipolysis by lipoprotein lipase). (Gene Ontology, GO_0034365)
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36 proteins co-occuring with the discoidal high-density lipoprotein particle cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
LPA lipoprotein, Lp(a) 2.6076
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 2.41749
APOA1 apolipoprotein A-I 2.25739
LCAT lecithin-cholesterol acyltransferase 2.09327
PLTP phospholipid transfer protein 1.45138
APOE apolipoprotein E 1.28196
APOA2 apolipoprotein A-II 1.26392
CETP cholesteryl ester transfer protein, plasma 1.15467
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.768627
SCARB1 scavenger receptor class B, member 1 0.728836
APOB apolipoprotein B 0.638861
APOC1 apolipoprotein C-I 0.617982
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 0.552664
LIPG lipase, endothelial 0.536183
OSBPL8 oxysterol binding protein-like 8 0.527979
LPL lipoprotein lipase 0.504318
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 0.461199
APOM apolipoprotein M 0.427497
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 0.407919
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.393549
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 0.379276
LDLR low density lipoprotein receptor 0.343421
SPINK5 serine peptidase inhibitor, Kazal type 5 0.330966
IRF6 interferon regulatory factor 6 0.329084
HDX highly divergent homeobox 0.327956
IGBP1 immunoglobulin (CD79A) binding protein 1 0.2719
HDLBP high density lipoprotein binding protein 0.244962
PHEX phosphate regulating endopeptidase homolog, X-linked 0.214366
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.208825
MPO myeloperoxidase 0.188274
MSRA methionine sulfoxide reductase A 0.185469
PON1 paraoxonase 1 0.177724
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 0.165463
ACACA acetyl-CoA carboxylase alpha 0.165231
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.160254
APOC3 apolipoprotein C-III 0.157578