diethylstilbestrol-4547 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the diethylstilbestrol-4547 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AADAC arylacetamide deacetylase
ADAP2 ArfGAP with dual PH domains 2
AGER advanced glycosylation end product-specific receptor
AKAP13 A kinase (PRKA) anchor protein 13
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ANGPTL4 angiopoietin-like 4
ATF3 activating transcription factor 3
ATP10A ATPase, class V, type 10A
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTN3A2 butyrophilin, subfamily 3, member A2
C18ORF25 chromosome 18 open reading frame 25
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHI3L2 chitinase 3-like 2
CISH cytokine inducible SH2-containing protein
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EDN1 endothelin 1
EML2 echinoderm microtubule associated protein like 2
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
FGF5 fibroblast growth factor 5
FH fumarate hydratase
FLT1 fms-related tyrosine kinase 1
FOXF1 forkhead box F1
FOXO4 forkhead box O4
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA4 GATA binding protein 4
GFOD2 glucose-fructose oxidoreductase domain containing 2
GK glycerol kinase
HES2 hes family bHLH transcription factor 2
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICA1 islet cell autoantigen 1, 69kDa
IL24 interleukin 24
IQCK IQ motif containing K
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KDM5A lysine (K)-specific demethylase 5A
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIF1C kinesin family member 1C
LIG4 ligase IV, DNA, ATP-dependent
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRP1 low density lipoprotein receptor-related protein 1
MAP2K7 mitogen-activated protein kinase kinase 7
MARK2 MAP/microtubule affinity-regulating kinase 2
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MLXIP MLX interacting protein
MMP15 matrix metallopeptidase 15 (membrane-inserted)
NEBL nebulette
NF1 neurofibromin 1
NRN1 neuritin 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
PARP6 poly (ADP-ribose) polymerase family, member 6
PBOV1 prostate and breast cancer overexpressed 1
PCDHB3 protocadherin beta 3
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFA platelet-derived growth factor alpha polypeptide
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRDM2 PR domain containing 2, with ZNF domain
PTCH2 patched 2
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RASAL2 RAS protein activator like 2
RBM48 RNA binding motif protein 48
RGS6 regulator of G-protein signaling 6
RNF6 ring finger protein (C3H2C3 type) 6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUFY3 RUN and FYVE domain containing 3
SAYSD1 SAYSVFN motif domain containing 1
SCEL sciellin
SCYL2 SCY1-like 2 (S. cerevisiae)
SEMG2 semenogelin II
SETD3 SET domain containing 3
SGK2 serum/glucocorticoid regulated kinase 2
SHOX2 short stature homeobox 2
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLN sarcolipin
SPRR3 small proline-rich protein 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK17B serine/threonine kinase 17b
THOC5 THO complex 5
TLE4 transducin-like enhancer of split 4
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TPM2 tropomyosin 2 (beta)
TRAF4 TNF receptor-associated factor 4
TTC12 tetratricopeptide repeat domain 12
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
VGF VGF nerve growth factor inducible
VIPR2 vasoactive intestinal peptide receptor 2
ZNF155 zinc finger protein 155
ZNF280B zinc finger protein 280B

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABHD17B abhydrolase domain containing 17B
ACIN1 apoptotic chromatin condensation inducer 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALPK1 alpha-kinase 1
ANXA2P1 annexin A2 pseudogene 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ASTN2 astrotactin 2
ATAT1 alpha tubulin acetyltransferase 1
BAHD1 bromo adjacent homology domain containing 1
BFSP1 beaded filament structural protein 1, filensin
C17ORF70 chromosome 17 open reading frame 70
C19ORF40 chromosome 19 open reading frame 40
C1ORF159 chromosome 1 open reading frame 159
C3 complement component 3
CA5BP1 carbonic anhydrase VB pseudogene 1
CCDC9 coiled-coil domain containing 9
CCNJL cyclin J-like
CCP110 centriolar coiled coil protein 110kDa
CD101 CD101 molecule
CD70 CD70 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CLIC3 chloride intracellular channel 3
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CORO1A coronin, actin binding protein, 1A
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAL4 dynein, axonemal, light chain 4
DNM3 dynamin 3
DTX2 deltex 2, E3 ubiquitin ligase
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ERAP2 endoplasmic reticulum aminopeptidase 2
FANCC Fanconi anemia, complementation group C
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GLS2 glutaminase 2 (liver, mitochondrial)
GRTP1 growth hormone regulated TBC protein 1
HDAC7 histone deacetylase 7
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2BN histone cluster 1, H2bn
HOXA1 homeobox A1
HOXA7 homeobox A7
HOXC4 homeobox C4
HYAL3 hyaluronoglucosaminidase 3
IRF1 interferon regulatory factor 1
KDM7A lysine (K)-specific demethylase 7A
KIAA0319L KIAA0319-like
KLF3 Kruppel-like factor 3 (basic)
LOC390998 ribosomal protein L10 pseudogene
LOC729164 hCG1732469
LY6D lymphocyte antigen 6 complex, locus D
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MFSD11 major facilitator superfamily domain containing 11
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MX1 MX dynamin-like GTPase 1
NDRG4 NDRG family member 4
NKX3-2 NK3 homeobox 2
NPFFR1 neuropeptide FF receptor 1
ODF2 outer dense fiber of sperm tails 2
OSBP2 oxysterol binding protein 2
OVGP1 oviductal glycoprotein 1, 120kDa
PALMD palmdelphin
PLAT plasminogen activator, tissue
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRR15L proline rich 15-like
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTPRS protein tyrosine phosphatase, receptor type, S
RANBP17 RAN binding protein 17
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RPS17P5 ribosomal protein S17 pseudogene 5
SDC3 syndecan 3
SEPP1 selenoprotein P, plasma, 1
SH2D4A SH2 domain containing 4A
SLMO1 slowmo homolog 1 (Drosophila)
SMR3A submaxillary gland androgen regulated protein 3A
SREBF1 sterol regulatory element binding transcription factor 1
SYT17 synaptotagmin XVII
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCTN2 tectonic family member 2
TENM1 teneurin transmembrane protein 1
TEP1 telomerase-associated protein 1
TLR2 toll-like receptor 2
TMEM19 transmembrane protein 19
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRIM21 tripartite motif containing 21
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPC5 transient receptor potential cation channel, subfamily C, member 5
USP19 ubiquitin specific peptidase 19
ZNF37BP zinc finger protein 37B, pseudogene
ZNF768 zinc finger protein 768
ZNHIT2 zinc finger, HIT-type containing 2