diarrhea Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A gastrointestinal system disease described as the condition of having frequent loose or liquid bowel movements. Acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide. The loss of fluids through diarrhea can cause severe dehydration which is one cause of death in diarrhea sufferers. Along with water, sufferers also lose dangerous amounts of important salts, electrolytes, and other nutrients. There are at least four types of diarrhea: secretory diarrhea, osmotic diarrhea, motility-related diarrhea, and inflammatory diarrhea. (Human Disease Ontology, DOID_13250)
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Genes

714 genes co-occuring with the disease diarrhea in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 2.29358
STX2 syntaxin 2 2.25425
LCT lactase 2.18978
CD79A CD79a molecule, immunoglobulin-associated alpha 2.10281
STX1A syntaxin 1A (brain) 2.0518
CD4 CD4 molecule 2.0311
SST somatostatin 2.02929
EGFR epidermal growth factor receptor 1.91127
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.8899
SLC26A3 solute carrier family 26 (anion exchanger), member 3 1.85866
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.82323
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.82323
ALB albumin 1.80968
VIP vasoactive intestinal peptide 1.7903
GAST gastrin 1.75913
TOP1 topoisomerase (DNA) I 1.68498
ICT1 immature colon carcinoma transcript 1 1.68317
SH2D3A SH2 domain containing 3A 1.62649
ALPPL2 alkaline phosphatase, placental-like 2 1.61173
ALPP alkaline phosphatase, placental 1.61128
ALPL alkaline phosphatase, liver/bone/kidney 1.61039
SUMF2 sulfatase modifying factor 2 1.60726
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.57735
DPYD dihydropyrimidine dehydrogenase 1.55734
CDAN1 codanin 1 1.54982
LTF lactotransferrin 1.54716
SH2D3C SH2 domain containing 3C 1.5326
CSHL1 chorionic somatomammotropin hormone-like 1 1.52512
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.51325
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.50491
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.48955
PPY pancreatic polypeptide 1.47023
RNF112 ring finger protein 112 1.46012
SI sucrase-isomaltase (alpha-glucosidase) 1.45704
GUCY2C guanylate cyclase 2C 1.4342
FAM20C family with sequence similarity 20, member C 1.4206
ERBB2 erb-b2 receptor tyrosine kinase 2 1.4184
CRP C-reactive protein, pentraxin-related 1.41358
TOX thymocyte selection-associated high mobility group box 1.39957
CPE carboxypeptidase E 1.37643
ALLC allantoicase 1.3494
TYMS thymidylate synthetase 1.34592
PYY peptide YY 1.33894
NPR1 natriuretic peptide receptor 1 1.32541
MLN motilin 1.31275
CSN1S1 casein alpha s1 1.28523
PI3 peptidase inhibitor 3, skin-derived 1.26865
PPT2 palmitoyl-protein thioesterase 2 1.25602
MYO5B myosin VB 1.24645
TAC1 tachykinin, precursor 1 1.24428
ZNF185 zinc finger protein 185 (LIM domain) 1.2382
INS insulin 1.23039
GCG glucagon 1.22518
TTC37 tetratricopeptide repeat domain 37 1.21652
CHGA chromogranin A 1.21608
APOLD1 apolipoprotein L domain containing 1 1.21565
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.21478
OCLN occludin 1.21262
KRAS Kirsten rat sarcoma viral oncogene homolog 1.19921
MPO myeloperoxidase 1.19834
TNF tumor necrosis factor 1.19402
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.19229
TTR transthyretin 1.19014
CALCA calcitonin-related polypeptide alpha 1.18367
LTB lymphotoxin beta (TNF superfamily, member 3) 1.17378
IL2 interleukin 2 1.1605
TJP1 tight junction protein 1 1.1473
CAMP cathelicidin antimicrobial peptide 1.13416
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.12572
IGHV1-2 immunoglobulin heavy variable 1-2 1.11687
IFNA1 interferon, alpha 1 1.11225
BCHE butyrylcholinesterase 1.09713
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 1.09629
CELA1 chymotrypsin-like elastase family, member 1 1.09587
F2 coagulation factor II (thrombin) 1.08999
CELA3B chymotrypsin-like elastase family, member 3B 1.08454
CDH3 cadherin 3, type 1, P-cadherin (placental) 1.06564
CCK cholecystokinin 1.05345
MME membrane metallo-endopeptidase 1.04798
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 1.04714
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.01976
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 1.01765
GGT1 gamma-glutamyltransferase 1 1.01723
MGAM maltase-glucoamylase 1.01723
KLK3 kallikrein-related peptidase 3 1.01047
CLDN1 claudin 1 1.00794
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 1.0033
DLL1 delta-like 1 (Drosophila) 0.993596
ETHE1 ethylmalonic encephalopathy 1 0.979268
FGF19 fibroblast growth factor 19 0.978426
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.97338
HRAS Harvey rat sarcoma viral oncogene homolog 0.97254
CLDN7 claudin 7 0.97212
CSF3 colony stimulating factor 3 (granulocyte) 0.9717
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 0.9717
NTS neurotensin 0.967921
TMPRSS15 transmembrane protease, serine 15 0.962891
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.95745
IFNA2 interferon, alpha 2 0.95745
ACHE acetylcholinesterase (Yt blood group) 0.956196
MGP matrix Gla protein 0.954108
TPI1 triosephosphate isomerase 1 0.954108
TF transferrin 0.95369
SLC39A4 solute carrier family 39 (zinc transporter), member 4 0.94577
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.942027
PHB2 prohibitin 2 0.940364
EPGN epithelial mitogen 0.938704
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 0.936629
IL1B interleukin 1, beta 0.932898
STX1B syntaxin 1B 0.929173
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.91308
WASH7P WAS protein family homolog 7 pseudogene 0.912257
CXCL8 chemokine (C-X-C motif) ligand 8 0.911022
WASH1 WAS protein family homolog 1 0.908142
WASH6P WAS protein family homolog 6 pseudogene 0.905265
COMT catechol-O-methyltransferase 0.898282
RPS19BP1 ribosomal protein S19 binding protein 1 0.897461
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.896641
TFF3 trefoil factor 3 (intestinal) 0.894179
TYMP thymidine phosphorylase 0.891718
DNAH8 dynein, axonemal, heavy chain 8 0.889258
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.888438
MUC13 mucin 13, cell surface associated 0.88475
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 0.877376
KSR1 kinase suppressor of ras 1 0.876557
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 0.871234
SEMG1 semenogelin I 0.859771
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7 0.851992
GUSB glucuronidase, beta 0.847898
PER1 period circadian clock 1 0.843802
MUC20 mucin 20, cell surface associated 0.842163
HRH2 histamine receptor H2 0.841753
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 0.836427
SHF Src homology 2 domain containing F 0.828639
ITM2B integral membrane protein 2B 0.827409
TPH1 tryptophan hydroxylase 1 0.824948
PDZD3 PDZ domain containing 3 0.820847
IFI30 interferon, gamma-inducible protein 30 0.818796
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.816334
CPB2 carboxypeptidase B2 (plasma) 0.815924
CABIN1 calcineurin binding protein 1 0.811001
EBF1 early B-cell factor 1 0.808539
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.807308
PDGFB platelet-derived growth factor beta polypeptide 0.805667
RET ret proto-oncogene 0.801154
SAR1B secretion associated, Ras related GTPase 1B 0.801154
LYZ lysozyme 0.794181
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 0.794181
POMC proopiomelanocortin 0.792541
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.792131
SLC26A6 solute carrier family 26 (anion exchanger), member 6 0.791721
PID1 phosphotyrosine interaction domain containing 1 0.786394
KLB klotho beta 0.783936
MVK mevalonate kinase 0.777386
FOXP3 forkhead box P3 0.770844
NONO non-POU domain containing, octamer-binding 0.766351
IL10 interleukin 10 0.765943
F3 coagulation factor III (thromboplastin, tissue factor) 0.756564
CDSN corneodesmosin 0.755342
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.753713
PER2 period circadian clock 2 0.75005
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 0.742735
ACE angiotensin I converting enzyme 0.742329
TSPO translocator protein (18kDa) 0.740299
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.740299
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.73746
CYGB cytoglobin 0.734622
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.732596
CRH corticotropin releasing hormone 0.730571
LALBA lactalbumin, alpha- 0.730166
KDR kinase insert domain receptor 0.729762
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.729357
CAT catalase 0.724907
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 0.723694
FTH1 ferritin, heavy polypeptide 1 0.718443
VEGFA vascular endothelial growth factor A 0.716021
LCK LCK proto-oncogene, Src family tyrosine kinase 0.716021
SLC25A47 solute carrier family 25, member 47 0.713198
EPN2 epsin 2 0.71078
PARP1 poly (ADP-ribose) polymerase 1 0.710378
CCL20 chemokine (C-C motif) ligand 20 0.708364
FTL ferritin, light polypeptide 0.706754
DCLRE1C DNA cross-link repair 1C 0.706351
EQTN equatorin, sperm acrosome associated 0.705144
IGF1 insulin-like growth factor 1 (somatomedin C) 0.705144
HBG1 hemoglobin, gamma A 0.70233
ALPI alkaline phosphatase, intestinal 0.698313
OPRM1 opioid receptor, mu 1 0.697911
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.693098
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.692697
MUC4 mucin 4, cell surface associated 0.691896
PDE4A phosphodiesterase 4A, cAMP-specific 0.691495
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.686291
ANPEP alanyl (membrane) aminopeptidase 0.680697
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.675112
NPY neuropeptide Y 0.675112
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 0.674713
REN renin 0.67113
GLP1R glucagon-like peptide 1 receptor 0.67113
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.66914
NPS neuropeptide S 0.668742
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.668742
SNX18 sorting nexin 18 0.661594
TREH trehalase (brush-border membrane glycoprotein) 0.659611
DPT dermatopontin 0.659611
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.658422
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.658422
IL6 interleukin 6 0.653671
MEN1 multiple endocrine neoplasia I 0.653276
CNR1 cannabinoid receptor 1 (brain) 0.649718
PTH parathyroid hormone 0.648928
GIP gastric inhibitory polypeptide 0.647743
SAA1 serum amyloid A1 0.64577
FLNA filamin A, alpha 0.644586
MUC2 mucin 2, oligomeric mucus/gel-forming 0.644586
DHFR dihydrofolate reductase 0.644192
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.641827
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 0.640251
NOS2 nitric oxide synthase 2, inducible 0.639857
HLA-C major histocompatibility complex, class I, C 0.636315
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.635135
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 0.632384
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.631598
ERVW-1 endogenous retrovirus group W, member 1 0.62885
DTX1 deltex 1, E3 ubiquitin ligase 0.623359
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 0.622183
NEUROG3 neurogenin 3 0.621792
ANTXR2 anthrax toxin receptor 2 0.621008
HN1 hematological and neurological expressed 1 0.619442
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 0.619442
LAP3 leucine aminopeptidase 3 0.617486
TRH thyrotropin-releasing hormone 0.614747
HP haptoglobin 0.614356
SOD2 superoxide dismutase 2, mitochondrial 0.613183
DPP4 dipeptidyl-peptidase 4 0.611229
CLDN4 claudin 4 0.611229
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 0.610057
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 0.608104
HPR haptoglobin-related protein 0.607714
C3 complement component 3 0.607714
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5 0.606933
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.605762
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 0.605372
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 0.604981
CALCOCO2 calcium binding and coiled-coil domain 2 0.60225
CRHR1 corticotropin releasing hormone receptor 1 0.60069
PDZD11 PDZ domain containing 11 0.590558
NAAA N-acylethanolamine acid amidase 0.589779
RAB3D RAB3D, member RAS oncogene family 0.589001
DHODH dihydroorotate dehydrogenase (quinone) 0.586276
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.585108
LY96 lymphocyte antigen 96 0.583163
PIGR polymeric immunoglobulin receptor 0.579661
PER3 period circadian clock 3 0.579272
AQP3 aquaporin 3 (Gill blood group) 0.578883
HSF4 heat shock transcription factor 4 0.578106
ANO1 anoctamin 1, calcium activated chloride channel 0.575772
FOS FBJ murine osteosarcoma viral oncogene homolog 0.575772
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.573828
PNLIP pancreatic lipase 0.573828
CFB complement factor B 0.571107
PDZK1 PDZ domain containing 1 0.571107
FUT2 fucosyltransferase 2 (secretor status included) 0.569163
CXCL2 chemokine (C-X-C motif) ligand 2 0.568386
CEMP1 cementum protein 1 0.567997
CD34 CD34 molecule 0.560616
KNG1 kininogen 1 0.560227
FAM210B family with sequence similarity 210, member B 0.559839
VWF von Willebrand factor 0.55945
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.558674
PRKG2 protein kinase, cGMP-dependent, type II 0.557897
SLC26A5 solute carrier family 26 (anion exchanger), member 5 0.554015
AQP8 aquaporin 8 0.552463
SYNRG synergin, gamma 0.544318
TRIM37 tripartite motif containing 37 0.543155
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.541605
PIDD1 p53-induced death domain protein 1 0.538893
HSPA4 heat shock 70kDa protein 4 0.537344
SORBS2 sorbin and SH3 domain containing 2 0.531541
CD248 CD248 molecule, endosialin 0.529608
SLCO1B1 solute carrier organic anion transporter family, member 1B1 0.526904
PNN pinin, desmosome associated protein 0.526904
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.526904
ACRC acidic repeat containing 0.522659
FABP6 fatty acid binding protein 6, ileal 0.522659
ENO2 enolase 2 (gamma, neuronal) 0.519575
TLR2 toll-like receptor 2 0.51842
ZHX2 zinc fingers and homeoboxes 2 0.51611
CD40LG CD40 ligand 0.514571
SETD1A SET domain containing 1A 0.512264
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.509192
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 0.50689
B2M beta-2-microglobulin 0.504973
CLDN3 claudin 3 0.504973
MYLK myosin light chain kinase 0.504973
NCAM2 neural cell adhesion molecule 2 0.501909
PGF placental growth factor 0.501527
AQP10 aquaporin 10 0.501144
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.499231
ERBB4 erb-b2 receptor tyrosine kinase 4 0.497703
PCSK1 proprotein convertase subtilisin/kexin type 1 0.496939
GP2 glycoprotein 2 (zymogen granule membrane) 0.496175
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.495029
BTK Bruton agammaglobulinemia tyrosine kinase 0.493503
TLR5 toll-like receptor 5 0.491978
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.491215
RPS3 ribosomal protein S3 0.48893
CES2 carboxylesterase 2 0.483604
DIABLO diablo, IAP-binding mitochondrial protein 0.482844
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.479807
CPB1 carboxypeptidase B1 (tissue) 0.479427
FLT3 fms-related tyrosine kinase 3 0.478668
PPCS phosphopantothenoylcysteine synthetase 0.47753
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 0.467306
GPX5 glutathione peroxidase 5 0.466172
NKTR natural killer cell triggering receptor 0.463905
NCAM1 neural cell adhesion molecule 1 0.463527
CD46 CD46 molecule, complement regulatory protein 0.463149
GPX4 glutathione peroxidase 4 0.463149
CXCL3 chemokine (C-X-C motif) ligand 3 0.460883
MPI mannose phosphate isomerase 0.460506
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.458996
HEG1 heart development protein with EGF-like domains 1 0.457109
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.452208
GGT2 gamma-glutamyltransferase 2 0.451454
RNF25 ring finger protein 25 0.448441
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.448064
GPX1 glutathione peroxidase 1 0.447687
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 0.445805
ICAM1 intercellular adhesion molecule 1 0.443923
TLR4 toll-like receptor 4 0.441666
CDC42 cell division cycle 42 0.439786
SLC26A8 solute carrier family 26 (anion exchanger), member 8 0.43753
MTTP microsomal triglyceride transfer protein 0.437154
TACR2 tachykinin receptor 2 0.436778
CFH complement factor H 0.430017
MUC3A mucin 3A, cell surface associated 0.42814
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 0.427765
OPRK1 opioid receptor, kappa 1 0.427015
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.425514
ARSI arylsulfatase family, member I 0.424014
GCC2 GRIP and coiled-coil domain containing 2 0.42289
JUN jun proto-oncogene 0.420641
IGLV2-8 immunoglobulin lambda variable 2-8 0.418768
DCXR dicarbonyl/L-xylulose reductase 0.416521
OR6B2 olfactory receptor, family 6, subfamily B, member 2 0.416147
ARMC9 armadillo repeat containing 9 0.413901
GAL galanin/GMAP prepropeptide 0.412405
FGFR4 fibroblast growth factor receptor 4 0.40904
GLB1 galactosidase, beta 1 0.408292
PFN2 profilin 2 0.405678
IL4 interleukin 4 0.402318
C8ORF34 chromosome 8 open reading frame 34 0.401572
FAM132A family with sequence similarity 132, member A 0.400826
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.399707
DGAT1 diacylglycerol O-acyltransferase 1 0.398962
FAM83H family with sequence similarity 83, member H 0.398216
CLCA4 chloride channel accessory 4 0.397098
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 0.395235
PYGO1 pygopus family PHD finger 1 0.394863
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 0.393746
DNASE1L1 deoxyribonuclease I-like 1 0.391885
APOB apolipoprotein B 0.390025
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.389653
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.389281
GPBAR1 G protein-coupled bile acid receptor 1 0.387794
MEFV Mediterranean fever 0.387423
CD19 CD19 molecule 0.387051
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.387051
SLC30A2 solute carrier family 30 (zinc transporter), member 2 0.385565
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.385193
GUCA2B guanylate cyclase activator 2B (uroguanylin) 0.384822
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 0.384079
ERCC1 excision repair cross-complementation group 1 0.382223
ADORA1 adenosine A1 receptor 0.381852
BATF2 basic leucine zipper transcription factor, ATF-like 2 0.380739
SEPT10 septin 10 0.379626
DMBX1 diencephalon/mesencephalon homeobox 1 0.379256
OXR1 oxidation resistance 1 0.378885
ERBB3 erb-b2 receptor tyrosine kinase 3 0.377773
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.377773
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 0.374438
SLC26A7 solute carrier family 26 (anion exchanger), member 7 0.373328
SYK spleen tyrosine kinase 0.370368
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.368518
MRAP melanocortin 2 receptor accessory protein 0.368149
AVP arginine vasopressin 0.367779
WDFY2 WD repeat and FYVE domain containing 2 0.36704
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene) 0.361502
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 0.361502
IL1A interleukin 1, alpha 0.360026
DNTT DNA nucleotidylexotransferase 0.360026
CTSA cathepsin A 0.359657
PITX1 paired-like homeodomain 1 0.359289
GSE1 Gse1 coiled-coil protein 0.358183
SELV selenoprotein V 0.358183
POLK polymerase (DNA directed) kappa 0.358183
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 0.357446
CLCA2 chloride channel accessory 2 0.356341
GIF gastric intrinsic factor (vitamin B synthesis) 0.354499
LPO lactoperoxidase 0.353763
SRY sex determining region Y 0.352291
LCTL lactase-like 0.351923
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.351555
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.347144
AOX1 aldehyde oxidase 1 0.344574
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 0.342739
CAV1 caveolin 1, caveolae protein, 22kDa 0.342006
PRB3 proline-rich protein BstNI subfamily 3 0.340906
BIN3 bridging integrator 3 0.340539
RAG2 recombination activating gene 2 0.33944
UTP15 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae) 0.339073
SYP synaptophysin 0.339073
OR6C2 olfactory receptor, family 6, subfamily C, member 2 0.338341
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.337242
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) 0.335778
SLC30A5 solute carrier family 30 (zinc transporter), member 5 0.334681
TPRG1L tumor protein p63 regulated 1-like 0.334681
DAXX death-domain associated protein 0.333949
UMPS uridine monophosphate synthetase 0.333583
IL3 interleukin 3 0.331025
CD68 CD68 molecule 0.329565
SIX3 SIX homeobox 3 0.328834
C6ORF25 chromosome 6 open reading frame 25 0.326281
TP53 tumor protein p53 0.325916
PTEN phosphatase and tensin homolog 0.325552
RTP1 receptor (chemosensory) transporter protein 1 0.32373
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.321909
LUM lumican 0.32009
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.318999
ESR1 estrogen receptor 1 0.318272
GHRL ghrelin/obestatin prepropeptide 0.318272
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.316456
ASRGL1 asparaginase like 1 0.314278
SOCS7 suppressor of cytokine signaling 7 0.31029
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.307757
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.306672
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 0.305587
GLS2 glutaminase 2 (liver, mitochondrial) 0.304864
STX3 syntaxin 3 0.303781
FN1 fibronectin 1 0.301976
DKKL1 dickkopf-like 1 0.300894
EID2B EP300 interacting inhibitor of differentiation 2B 0.300173
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.297651
ADPRH ADP-ribosylarginine hydrolase 0.296931
ODC1 ornithine decarboxylase 1 0.296211
GAS2 growth arrest-specific 2 0.294772
HAND1 heart and neural crest derivatives expressed 1 0.294772
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 0.293694
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 0.293334
EPN3 epsin 3 0.292257
DTX3 deltex 3, E3 ubiquitin ligase 0.292257
CP ceruloplasmin (ferroxidase) 0.291539
GRP gastrin-releasing peptide 0.289027
FGB fibrinogen beta chain 0.288668
IGLL5 immunoglobulin lambda-like polypeptide 5 0.287952
DERA deoxyribose-phosphate aldolase (putative) 0.287952
EPCAM epithelial cell adhesion molecule 0.286519
PEX10 peroxisomal biogenesis factor 10 0.283297
DPEP1 dipeptidase 1 (renal) 0.282582
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.279724
GSTA3 glutathione S-transferase alpha 3 0.27794
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.27794
CDA cytidine deaminase 0.277227
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.275445
PRAMEF20 PRAME family member 20 0.275445
MLX MLX, MAX dimerization protein 0.274732
PYGB phosphorylase, glycogen; brain 0.274021
A1BG alpha-1-B glycoprotein 0.272953
USP50 ubiquitin specific peptidase 50 0.272597
ZNF135 zinc finger protein 135 0.272597
GCC1 GRIP and coiled-coil domain containing 1 0.271174
PYGL phosphorylase, glycogen, liver 0.270819
PPARG peroxisome proliferator-activated receptor gamma 0.270108
OR5K1 olfactory receptor, family 5, subfamily K, member 1 0.269753
UPP1 uridine phosphorylase 1 0.269398
NOD2 nucleotide-binding oligomerization domain containing 2 0.269043
IL2RA interleukin 2 receptor, alpha 0.267267
MLNR motilin receptor 0.266913
ARRB1 arrestin, beta 1 0.265849
ZNF77 zinc finger protein 77 0.265494
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.264077
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.264077
PNOC prepronociceptin 0.263368
USP32 ubiquitin specific peptidase 32 0.261952
IL1RN interleukin 1 receptor antagonist 0.260891
MGLL monoglyceride lipase 0.25877
SLC12A8 solute carrier family 12, member 8 0.258064
MOGS mannosyl-oligosaccharide glucosidase 0.258064
LPAR2 lysophosphatidic acid receptor 2 0.257711
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.257711
ERMP1 endoplasmic reticulum metallopeptidase 1 0.256299
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 0.256299
MYD88 myeloid differentiation primary response 88 0.255946
TFRC transferrin receptor 0.254888
CNOT8 CCR4-NOT transcription complex, subunit 8 0.253831
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.253831
SRL sarcalumenin 0.253479
CLCA1 chloride channel accessory 1 0.250663
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.247501
PYGM phosphorylase, glycogen, muscle 0.246448
OR10R2 olfactory receptor, family 10, subfamily R, member 2 0.246098
GSTA2 glutathione S-transferase alpha 2 0.245747
FBXL20 F-box and leucine-rich repeat protein 20 0.245396
USP9X ubiquitin specific peptidase 9, X-linked 0.245046
GSTA4 glutathione S-transferase alpha 4 0.244696
ADA adenosine deaminase 0.243645
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.241895
LSR lipolysis stimulated lipoprotein receptor 0.241546
STXBP2 syntaxin binding protein 2 0.240497
GSTA1 glutathione S-transferase alpha 1 0.23945
ARX aristaless related homeobox 0.238752
CD1E CD1e molecule 0.238752
CD80 CD80 molecule 0.237009
MB myoglobin 0.23666
HSFX2 heat shock transcription factor family, X linked 2 0.23353
HSFX1 heat shock transcription factor family, X linked 1 0.23353
SBDS Shwachman-Bodian-Diamond syndrome 0.232836
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.232489
PTGES prostaglandin E synthase 0.231448
MAPK14 mitogen-activated protein kinase 14 0.22937
POLR1C polymerase (RNA) I polypeptide C, 30kDa 0.228679
DAND5 DAN domain family member 5, BMP antagonist 0.228333
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.226607
MFGE8 milk fat globule-EGF factor 8 protein 0.226262
TCN2 transcobalamin II 0.225917
CARD17 caspase recruitment domain family, member 17 0.225917
FBXO44 F-box protein 44 0.225229
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.224884
SLCO2A1 solute carrier organic anion transporter family, member 2A1 0.224884
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 0.22454
GTDC1 glycosyltransferase-like domain containing 1 0.223509
DYNLRB1 dynein, light chain, roadblock-type 1 0.223165
HPN hepsin 0.223165
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.222822
RGMB repulsive guidance molecule family member b 0.222479
FGF1 fibroblast growth factor 1 (acidic) 0.220424
DOCK8 dedicator of cytokinesis 8 0.220424
AQP4 aquaporin 4 0.218715
AFP alpha-fetoprotein 0.218374
HTRA3 HtrA serine peptidase 3 0.218034
ARF6 ADP-ribosylation factor 6 0.218034
PRAMEF6 PRAME family member 6 0.216672
TGFB1 transforming growth factor, beta 1 0.214975
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.214297
MARS2 methionyl-tRNA synthetase 2, mitochondrial 0.213959
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 0.213959
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.213283
AKTIP AKT interacting protein 0.212945
METAP2 methionyl aminopeptidase 2 0.211597
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.211597
NENF neudesin neurotrophic factor 0.210253
DEFB4A defensin, beta 4A 0.210253
ACR acrosin 0.210253
PLCD3 phospholipase C, delta 3 0.20658
TOP3A topoisomerase (DNA) III alpha 0.206248
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.206248
RECQL4 RecQ protein-like 4 0.205916
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.205585
RAB11A RAB11A, member RAS oncogene family 0.205254
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.205254
GLA galactosidase, alpha 0.204593
DCAF5 DDB1 and CUL4 associated factor 5 0.203933
PRF1 perforin 1 (pore forming protein) 0.203604
RBBP9 retinoblastoma binding protein 9 0.198709
TAS1R2 taste receptor, type 1, member 2 0.196779
SOS1 son of sevenless homolog 1 (Drosophila) 0.196139
STPG1 sperm-tail PG-rich repeat containing 1 0.19582
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.195501
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.193915
POLI polymerase (DNA directed) iota 0.192971
IL11 interleukin 11 0.192657
PRRC2A proline-rich coiled-coil 2A 0.191719
ACE2 angiotensin I converting enzyme 2 0.189551
CXCL5 chemokine (C-X-C motif) ligand 5 0.188938
SHKBP1 SH3KBP1 binding protein 1 0.188326
CCL2 chemokine (C-C motif) ligand 2 0.188022
GPR161 G protein-coupled receptor 161 0.188022
SEBOX SEBOX homeobox 0.188022
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.187113
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.186811
PDZRN3 PDZ domain containing ring finger 3 0.18621
ALK anaplastic lymphoma receptor tyrosine kinase 0.18591
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific 0.184424
OR13F1 olfactory receptor, family 13, subfamily F, member 1 0.182957
LCA10 lung carcinoma-associated 10 0.182086
SUCLG1 succinate-CoA ligase, alpha subunit 0.18151
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.181222
CCL1 chemokine (C-C motif) ligand 1 0.181222
CXCL17 chemokine (C-X-C motif) ligand 17 0.17952
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.17952
NXPH1 neurexophilin 1 0.179239
RER1 retention in endoplasmic reticulum sorting receptor 1 0.17896
MDH1 malate dehydrogenase 1, NAD (soluble) 0.17896
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 0.178682
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.177301
IARS isoleucyl-tRNA synthetase 0.177029
CD5 CD5 molecule 0.177029
PGR progesterone receptor 0.177029
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.176757
CGB chorionic gonadotropin, beta polypeptide 0.176757
CGB8 chorionic gonadotropin, beta polypeptide 8 0.176215
EEA1 early endosome antigen 1 0.176215
FLT1 fms-related tyrosine kinase 1 0.175679
CXCL10 chemokine (C-X-C motif) ligand 10 0.175411
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 0.175146
THBD thrombomodulin 0.175146
PNP purine nucleoside phosphorylase 0.175146
TACR1 tachykinin receptor 1 0.173832
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 0.173832
CSF1R colony stimulating factor 1 receptor 0.173314
HDAC9 histone deacetylase 9 0.173057
GPANK1 G patch domain and ankyrin repeats 1 0.173057
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.172799
HIBCH 3-hydroxyisobutyryl-CoA hydrolase 0.172038
CHIT1 chitinase 1 (chitotriosidase) 0.171785
L3MBTL1 l(3)mbt-like 1 (Drosophila) 0.171535
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.171036
ARHGAP15 Rho GTPase activating protein 15 0.170789
FAAH fatty acid amide hydrolase 0.170544
SRI sorcin 0.170544
PLCG1 phospholipase C, gamma 1 0.170544
SLC51B solute carrier family 51, beta subunit 0.169812
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.168617
RBM25 RNA binding motif protein 25 0.168617
ECI2 enoyl-CoA delta isomerase 2 0.168148
ELOVL6 ELOVL fatty acid elongase 6 0.167915
OR2H2 olfactory receptor, family 2, subfamily H, member 2 0.167224
DPYS dihydropyrimidinase 0.166995
NIT2 nitrilase family, member 2 0.166768
IFNGR1 interferon gamma receptor 1 0.166768
EXOSC3 exosome component 3 0.166319
PRDM16 PR domain containing 16 0.166095
VCAM1 vascular cell adhesion molecule 1 0.165217
CPSF3L cleavage and polyadenylation specific factor 3-like 0.164786
NT5E 5'-nucleotidase, ecto (CD73) 0.164359
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.164359
NOD1 nucleotide-binding oligomerization domain containing 1 0.164359
SMS spermine synthase 0.164149
CXXC5 CXXC finger protein 5 0.163729
DPP6 dipeptidyl-peptidase 6 0.163523
GRHL1 grainyhead-like 1 (Drosophila) 0.163111
UGCG UDP-glucose ceramide glucosyltransferase 0.162505
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.161912
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.161523
KIF16B kinesin family member 16B 0.160761
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.160574
TMPRSS13 transmembrane protease, serine 13 0.160574
CD37 CD37 molecule 0.160574
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.159838
FBLIM1 filamin binding LIM protein 1 0.159658
KRT9 keratin 9, type I 0.15948
ADCY2 adenylate cyclase 2 (brain) 0.158951
MARS methionyl-tRNA synthetase 0.158778
COX5A cytochrome c oxidase subunit Va 0.143863
HDAC11 histone deacetylase 11 0.143483
DERL1 derlin 1 0.143479
PRKG1 protein kinase, cGMP-dependent, type I 0.143082
PRELP proline/arginine-rich end leucine-rich repeat protein 0.141981
TRIM44 tripartite motif containing 44 0.141939
GOPC golgi-associated PDZ and coiled-coil motif containing 0.141905
CD48 CD48 molecule 0.141832
PARP14 poly (ADP-ribose) polymerase family, member 14 0.141804
CASD1 CAS1 domain containing 1 0.141721
SUB1 SUB1 homolog (S. cerevisiae) 0.141316
TTK TTK protein kinase 0.141258
MYO9B myosin IXB 0.14113
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.140698
LARS leucyl-tRNA synthetase 0.140521
GPR135 G protein-coupled receptor 135 0.14051
CFP complement factor properdin 0.139596
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.1395
MYO6 myosin VI 0.139383
CUTA cutA divalent cation tolerance homolog (E. coli) 0.139377
ALYREF Aly/REF export factor 0.139176
BEST1 bestrophin 1 0.13906
ADORA2B adenosine A2b receptor 0.138834
MMD monocyte to macrophage differentiation-associated 0.13802
FLOT1 flotillin 1 0.137359
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 0.137287
CLDN11 claudin 11 0.137009
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.136932
HAX1 HCLS1 associated protein X-1 0.136798
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.136651
FABP2 fatty acid binding protein 2, intestinal 0.13648
RAB8A RAB8A, member RAS oncogene family 0.135623
CALB1 calbindin 1, 28kDa 0.135336
CHEK1 checkpoint kinase 1 0.135086
BAX BCL2-associated X protein 0.135074
MRPL49 mitochondrial ribosomal protein L49 0.135026
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.134729
EMP1 epithelial membrane protein 1 0.13433
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 0.133473
SSTR1 somatostatin receptor 1 0.132383
CXCL16 chemokine (C-X-C motif) ligand 16 0.132351
IL18 interleukin 18 0.132104
IL17A interleukin 17A 0.131729
PTAFR platelet-activating factor receptor 0.131377
PDE4D phosphodiesterase 4D, cAMP-specific 0.130806
SSTR5 somatostatin receptor 5 0.130693
P4HB prolyl 4-hydroxylase, beta polypeptide 0.130577
NPPC natriuretic peptide C 0.129462
CHAT choline O-acetyltransferase 0.128601
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.128371
MAPK8 mitogen-activated protein kinase 8 0.128042
SGK1 serum/glucocorticoid regulated kinase 1 0.127872
MYO7A myosin VIIA 0.127404
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.124946
RUNX3 runt-related transcription factor 3 0.123902
SSTR2 somatostatin receptor 2 0.123191
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.122619
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.12079
KLK1 kallikrein 1 0.120409
NOG noggin 0.119349