diaphragm Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The thin muscle below the lungs and heart that separates the chest from the abdomen. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000341)
Similar Terms
Downloads & Tools

Genes

376 proteins co-occuring with the tissue diaphragm in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
ACHE acetylcholinesterase (Yt blood group) 2.28596
INS insulin 2.16602
BCHE butyrylcholinesterase 1.97571
DMD dystrophin 1.93991
CS citrate synthase 1.65007
FGFRL1 fibroblast growth factor receptor-like 1 1.58584
DNAH8 dynein, axonemal, heavy chain 8 1.52235
GAA glucosidase, alpha; acid 1.51569
RYR3 ryanodine receptor 3 1.48598
FBXO32 F-box protein 32 1.41537
XYLT1 xylosyltransferase I 1.32371
PFKM phosphofructokinase, muscle 1.32235
MYOD1 myogenic differentiation 1 1.23405
UTRN utrophin 1.21935
ALB albumin 1.21001
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 1.17713
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.17624
MYH4 myosin, heavy chain 4, skeletal muscle 1.15362
DMRTA1 DMRT-like family A1 1.14919
PYGL phosphorylase, glycogen, liver 1.14166
PYGB phosphorylase, glycogen; brain 1.1235
SOD2 superoxide dismutase 2, mitochondrial 1.11818
LPL lipoprotein lipase 1.11818
PAX3 paired box 3 1.11641
PYGM phosphorylase, glycogen, muscle 1.11641
RYR1 ryanodine receptor 1 (skeletal) 1.11154
MYOG myogenin (myogenic factor 4) 1.0859
MYBPC1 myosin binding protein C, slow type 1.0859
FTL ferritin, light polypeptide 1.06426
FTH1 ferritin, heavy polypeptide 1 1.05545
IGHMBP2 immunoglobulin mu binding protein 2 1.05149
MYL1 myosin, light chain 1, alkali; skeletal, fast 1.05104
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.03829
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 1.03434
PLVAP plasmalemma vesicle associated protein 1.01331
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 1.01331
ZFPM2 zinc finger protein, FOG family member 2 1.00981
IGF1 insulin-like growth factor 1 (somatomedin C) 1.00807
MUSK muscle, skeletal, receptor tyrosine kinase 0.990204
HADH hydroxyacyl-CoA dehydrogenase 0.98977
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.968523
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 0.95988
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 0.950393
LCN6 lipocalin 6 0.949531
PGPEP1L pyroglutamyl-peptidase I-like 0.940066
CCDC102B coiled-coil domain containing 102B 0.928478
MGAM maltase-glucoamylase 0.926336
F2 coagulation factor II (thrombin) 0.925907
GDAP1 ganglioside induced differentiation associated protein 1 0.922055
PLA2G1B phospholipase A2, group IB (pancreas) 0.907961
MYF5 myogenic factor 5 0.903701
GLRA2 glycine receptor, alpha 2 0.900296
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 0.898595
FAM151B family with sequence similarity 151, member B 0.896895
MIS18A MIS18 kinetochore protein A 0.896895
TTN titin 0.89477
SLC25A44 solute carrier family 25, member 44 0.881204
MSTN myostatin 0.877397
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 0.85505
GOLGA7 golgin A7 0.852527
LRTM1 leucine-rich repeats and transmembrane domains 1 0.851686
QDPR quinoid dihydropteridine reductase 0.851266
SLIT3 slit homolog 3 (Drosophila) 0.847904
AFP alpha-fetoprotein 0.844965
HEPHL1 hephaestin-like 1 0.844126
YIPF1 Yip1 domain family, member 1 0.826942
CAT catalase 0.817322
TCTE3 t-complex-associated-testis-expressed 3 0.813144
GPX1 glutathione peroxidase 1 0.811473
ZFPM1 zinc finger protein, FOG family member 1 0.806465
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.795208
PGRMC1 progesterone receptor membrane component 1 0.791877
FOXO1 forkhead box O1 0.791877
GPX5 glutathione peroxidase 5 0.790628
GPX4 glutathione peroxidase 4 0.786468
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.77857
MB myoglobin 0.77774
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 0.776909
PPIH peptidylprolyl isomerase H (cyclophilin H) 0.762811
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.753297
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.749166
NMT1 N-myristoyltransferase 1 0.741327
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.739678
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.737618
VCX variable charge, X-linked 0.730208
VCX2 variable charge, X-linked 2 0.724863
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 0.721166
VCX3B variable charge, X-linked 3B 0.71501
PNPLA6 patatin-like phospholipase domain containing 6 0.7146
RNF165 ring finger protein 165 0.70886
VCX3A variable charge, X-linked 3A 0.701899
CALCA calcitonin-related polypeptide alpha 0.697399
CST7 cystatin F (leukocystatin) 0.691268
SBF2 SET binding factor 2 0.688
WT1 Wilms tumor 1 0.688
GCG glucagon 0.685959
MAEA macrophage erythroblast attacher 0.685143
TNF tumor necrosis factor 0.684327
PXMP4 peroxisomal membrane protein 4, 24kDa 0.681064
TPM1 tropomyosin 1 (alpha) 0.676172
LAMA2 laminin, alpha 2 0.67495
GATA4 GATA binding protein 4 0.6721
HK1 hexokinase 1 0.658272
TEF thyrotrophic embryonic factor 0.651777
GJD4 gap junction protein, delta 4, 40.1kDa 0.65056
LBX1 ladybird homeobox 1 0.649749
MYF6 myogenic factor 6 (herculin) 0.647316
CASQ2 calsequestrin 2 (cardiac muscle) 0.643263
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.634762
CAST calpastatin 0.630314
CKM creatine kinase, muscle 0.628697
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 0.627485
SALL4 spalt-like transcription factor 4 0.625465
MLX MLX, MAX dimerization protein 0.624254
CHAT choline O-acetyltransferase 0.61941
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.612152
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.602088
NOS1 nitric oxide synthase 1 (neuronal) 0.589234
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.588832
FBXO45 F-box protein 45 0.587629
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.584823
NOTCH1 notch 1 0.583621
GPR176 G protein-coupled receptor 176 0.582019
INSR insulin receptor 0.580017
ALDOC aldolase C, fructose-bisphosphate 0.578016
MYH1 myosin, heavy chain 1, skeletal muscle, adult 0.574816
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.567626
ALDOB aldolase B, fructose-bisphosphate 0.567626
GLB1 galactosidase, beta 1 0.555671
DNM2 dynamin 2 0.54812
MEF2A myocyte enhancer factor 2A 0.545342
CCDC110 coiled-coil domain containing 110 0.545342
SSPN sarcospan 0.544549
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.542963
TPM2 tropomyosin 2 (beta) 0.54217
TDP1 tyrosyl-DNA phosphodiesterase 1 0.54217
TAT tyrosine aminotransferase 0.539
NOS3 nitric oxide synthase 3 (endothelial cell) 0.537416
FOXO4 forkhead box O4 0.53346
RAPSN receptor-associated protein of the synapse 0.53346
POMC proopiomelanocortin 0.531484
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 0.527534
TNNT2 troponin T type 2 (cardiac) 0.522405
TNNT1 troponin T type 1 (skeletal, slow) 0.521617
TMX3 thioredoxin-related transmembrane protein 3 0.521617
PRX periaxin 0.520829
GH1 growth hormone 1 0.519647
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 0.517678
FGFR2 fibroblast growth factor receptor 2 0.516497
FAR2 fatty acyl CoA reductase 2 0.516104
NIN ninein (GSK3B interacting protein) 0.509813
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 0.50942
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 0.509027
MET MET proto-oncogene, receptor tyrosine kinase 0.506672
MTMR2 myotubularin related protein 2 0.506279
TPM3 tropomyosin 3 0.505887
DYSF dysferlin 0.505102
ALDOA aldolase A, fructose-bisphosphate 0.505102
SNX10 sorting nexin 10 0.493745
TEX15 testis expressed 15 0.4914
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.485156
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.484766
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.483596
DCPS decapping enzyme, scavenger 0.482428
RAB3A RAB3A, member RAS oncogene family 0.480091
CLIP3 CAP-GLY domain containing linker protein 3 0.478923
WDFY2 WD repeat and FYVE domain containing 2 0.476201
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.475812
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K 0.47348
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.473092
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.471539
HLX H2.0-like homeobox 0.469987
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.465335
GRHL1 grainyhead-like 1 (Drosophila) 0.463787
HOXA5 homeobox A5 0.4634
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1 0.462239
HLA-DOB major histocompatibility complex, class II, DO beta 0.45374
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.451813
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 0.449116
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.447192
F9 coagulation factor IX 0.447192
MTM1 myotubularin 1 0.446038
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.444115
MDH1 malate dehydrogenase 1, NAD (soluble) 0.443731
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 0.440658
GPM6B glycoprotein M6B 0.439507
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.436822
DSEL dermatan sulfate epimerase-like 0.436822
TGFB1 transforming growth factor, beta 1 0.435672
DMPK dystrophia myotonica-protein kinase 0.43414
XIRP2 xin actin binding repeat containing 2 0.431843
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 0.424581
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.423054
UGP2 UDP-glucose pyrophosphorylase 2 0.423054
RPTN repetin 0.422673
ALPPL2 alkaline phosphatase, placental-like 2 0.420385
ALPL alkaline phosphatase, liver/bone/kidney 0.419623
SLN sarcolipin 0.419623
ALPP alkaline phosphatase, placental 0.418861
RARS arginyl-tRNA synthetase 0.415434
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.415053
XCL2 chemokine (C motif) ligand 2 0.41087
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.410491
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.407453
AMY2A amylase, alpha 2A (pancreatic) 0.404418
ZNF484 zinc finger protein 484 0.40328
NUTM1 NUT midline carcinoma, family member 1 0.402901
SYP synaptophysin 0.402901
MBNL3 muscleblind-like splicing regulator 3 0.397979
LBR lamin B receptor 0.396465
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 0.394953
ARHGAP17 Rho GTPase activating protein 17 0.393442
LAX1 lymphocyte transmembrane adaptor 1 0.393064
XIRP1 xin actin binding repeat containing 1 0.392309
CBX1 chromobox homolog 1 0.391176
KIF7 kinesin family member 7 0.389289
RPIA ribose 5-phosphate isomerase A 0.385896
SARS seryl-tRNA synthetase 0.385896
PNMA2 paraneoplastic Ma antigen 2 0.38552
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.385143
SYPL2 synaptophysin-like 2 0.384766
CALB2 calbindin 2 0.382884
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.381755
CD34 CD34 molecule 0.377621
ADGRL4 adhesion G protein-coupled receptor L4 0.37687
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.37687
FBXO17 F-box protein 17 0.37687
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 0.374618
PAPOLB poly(A) polymerase beta (testis specific) 0.371245
PADI3 peptidyl arginine deiminase, type III 0.370496
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.368624
TAC1 tachykinin, precursor 1 0.367502
CAV3 caveolin 3 0.366007
SLFN12 schlafen family member 12 0.364513
SYN2 synapsin II 0.36302
KIRREL kin of IRRE like (Drosophila) 0.359664
IGSF5 immunoglobulin superfamily, member 5 0.359292
HSPA1A heat shock 70kDa protein 1A 0.358546
RIN3 Ras and Rab interactor 3 0.357802
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 0.355198
FGF2 fibroblast growth factor 2 (basic) 0.354826
JMJD6 jumonji domain containing 6 0.354084
PPCS phosphopantothenoylcysteine synthetase 0.352598
TEPP testis, prostate and placenta expressed 0.350001
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.348889
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 0.348148
HIF3A hypoxia inducible factor 3, alpha subunit 0.347408
LIPC lipase, hepatic 0.347038
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 0.345928
CRAT carnitine O-acetyltransferase 0.344079
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.34371
MYL4 myosin, light chain 4, alkali; atrial, embryonic 0.339282
BAZ2A bromodomain adjacent to zinc finger domain, 2A 0.333396
PAX8 paired box 8 0.332661
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.330827
NEB nebulin 0.330827
HCCAT5 hepatocellular carcinoma associated transcript 5 (non-protein coding) 0.330094
RARA retinoic acid receptor, alpha 0.329727
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.328628
RAD23A RAD23 homolog A (S. cerevisiae) 0.325701
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.323509
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 0.323509
PRAMEF6 PRAME family member 6 0.322779
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.322779
PRSS30P protease, serine, 30, pseudogene 0.321685
PAX7 paired box 7 0.319863
MYBPH myosin binding protein H 0.319134
FOXO3 forkhead box O3 0.317315
DST dystonin 0.315135
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 0.315135
CDH10 cadherin 10, type 2 (T2-cadherin) 0.315135
RING1 ring finger protein 1 0.312595
RPS19 ribosomal protein S19 0.312595
FBXO11 F-box protein 11 0.312232
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.311145
KRT7 keratin 7, type II 0.310421
POU3F1 POU class 3 homeobox 1 0.309335
COL6A1 collagen, type VI, alpha 1 0.308974
RAB12 RAB12, member RAS oncogene family 0.308974
ANO1 anoctamin 1, calcium activated chloride channel 0.307889
SYN3 synapsin III 0.307528
FBXO44 F-box protein 44 0.30464
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 0.303919
SMN1 survival of motor neuron 1, telomeric 0.302118
MYH7 myosin, heavy chain 7, cardiac muscle, beta 0.301039
FREM1 FRAS1 related extracellular matrix 1 0.30032
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.299601
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 0.299601
HOMER3 homer scaffolding protein 3 0.298883
ZNF135 zinc finger protein 135 0.294939
FGF10 fibroblast growth factor 10 0.293866
CAMP cathelicidin antimicrobial peptide 0.293151
SYT1 synaptotagmin I 0.292793
TERF2 telomeric repeat binding factor 2 0.292793
MATN1 matrilin 1, cartilage matrix protein 0.289582
HOXC5 homeobox C5 0.289582
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.28887
IAPP islet amyloid polypeptide 0.287803
KCNIP2 Kv channel interacting protein 2 0.287447
BRD4 bromodomain containing 4 0.287447
TOX4 TOX high mobility group box family member 4 0.287447
NEIL2 nei endonuclease VIII-like 2 (E. coli) 0.287447
NKX2-1 NK2 homeobox 1 0.281776
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.279307
TOP2B topoisomerase (DNA) II beta 180kDa 0.278955
EYA4 EYA transcriptional coactivator and phosphatase 4 0.2779
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 0.276846
DCN decorin 0.273696
EED embryonic ectoderm development 0.273696
FGF22 fibroblast growth factor 22 0.270909
HOXD8 homeobox D8 0.267446
EPYC epiphycan 0.266757
ENO3 enolase 3 (beta, muscle) 0.266757
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.264353
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 0.262304
RPS6 ribosomal protein S6 0.260606
MBNL2 muscleblind-like splicing regulator 2 0.260606
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.260267
KNG1 kininogen 1 0.259254
ACE angiotensin I converting enzyme 0.258917
HSPB8 heat shock 22kDa protein 8 0.258917
NCK2 NCK adaptor protein 2 0.257907
CSAD cysteine sulfinic acid decarboxylase 0.257237
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 0.253578
SST somatostatin 0.252919
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 0.25259
SPTBN4 spectrin, beta, non-erythrocytic 4 0.251606
SMN2 survival of motor neuron 2, centromeric 0.249977
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 0.247079
GSK3B glycogen synthase kinase 3 beta 0.24676
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 0.24676
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.245491
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.24486
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 0.24486
TPI1 triosephosphate isomerase 1 0.244232
LIPG lipase, endothelial 0.244232
RPAP3 RNA polymerase II associated protein 3 0.242983
CELF4 CUGBP, Elav-like family member 4 0.242983
TMPO thymopoietin 0.239913
MATR3 matrin 3 0.239007
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 0.238706
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 0.238108
VDAC1 voltage-dependent anion channel 1 0.237513
RYR2 ryanodine receptor 2 (cardiac) 0.235748
ANKRD11 ankyrin repeat domain 11 0.234878
NHLH2 nescient helix loop helix 2 0.233162
NT5E 5'-nucleotidase, ecto (CD73) 0.232599
VEGFC vascular endothelial growth factor C 0.232599
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.232317
NT5M 5',3'-nucleotidase, mitochondrial 0.231482
TMX1 thioredoxin-related transmembrane protein 1 0.23011
PCP4 Purkinje cell protein 4 0.229299
ANGPTL1 angiopoietin-like 1 0.227186
IRS1 insulin receptor substrate 1 0.226155
KRT20 keratin 20, type I 0.223177
PLN phospholamban 0.222699
RAB3C RAB3C, member RAS oncogene family 0.221755
HBA2 hemoglobin, alpha 2 0.221755
TAS1R3 taste receptor, type 1, member 3 0.221291
NCOA1 nuclear receptor coactivator 1 0.221291
ARL2BP ADP-ribosylation factor-like 2 binding protein 0.220152
LOX lysyl oxidase 0.219047
ARID1B AT rich interactive domain 1B (SWI1-like) 0.217974
MINA MYC induced nuclear antigen 0.217554
TPGS2 tubulin polyglutamylase complex subunit 2 0.217346
FBXW2 F-box and WD repeat domain containing 2 0.216528
TNNT3 troponin T type 3 (skeletal, fast) 0.216325
IL6 interleukin 6 0.215534
PTPRE protein tyrosine phosphatase, receptor type, E 0.215147
CSN1S1 casein alpha s1 0.214017
ESR1 estrogen receptor 1 0.213833
PEX10 peroxisomal biogenesis factor 10 0.21365
DES desmin 0.213471
MLANA melan-A 0.213291
CTSD cathepsin D 0.212761
CARD8 caspase recruitment domain family, member 8 0.212586