dexamethasone-6271 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the dexamethasone-6271 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACVR1B activin A receptor, type IB
ALPK1 alpha-kinase 1
AMPD3 adenosine monophosphate deaminase 3
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ART1 ADP-ribosyltransferase 1
ARTN artemin
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAAT bile acid CoA:amino acid N-acyltransferase
C9ORF9 chromosome 9 open reading frame 9
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CALML3 calmodulin-like 3
CEP162 centrosomal protein 162kDa
CIC capicua transcriptional repressor
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COL1A1 collagen, type I, alpha 1
CRABP1 cellular retinoic acid binding protein 1
CRELD1 cysteine-rich with EGF-like domains 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFR3B EFR3 homolog B (S. cerevisiae)
EML2 echinoderm microtubule associated protein like 2
EXOC7 exocyst complex component 7
FBXL7 F-box and leucine-rich repeat protein 7
FGF2 fibroblast growth factor 2 (basic)
GAS7 growth arrest-specific 7
GOSR1 golgi SNAP receptor complex member 1
GPC1 glypican 1
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXD11 homeobox D11
IDI2-AS1 IDI2 antisense RNA 1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL4R interleukin 4 receptor
IRAK4 interleukin-1 receptor-associated kinase 4
IRF1 interferon regulatory factor 1
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGB4 integrin, beta 4
LAMP1 lysosomal-associated membrane protein 1
LHX6 LIM homeobox 6
LOC729164 hCG1732469
LPIN1 lipin 1
LPPR2 lipid phosphate phosphatase-related protein type 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LTBP4 latent transforming growth factor beta binding protein 4
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK7 mitogen-activated protein kinase 7
MFAP3L microfibrillar-associated protein 3-like
MKL1 megakaryoblastic leukemia (translocation) 1
MRPL41 mitochondrial ribosomal protein L41
MVD mevalonate (diphospho) decarboxylase
MYO9B myosin IXB
MYOF myoferlin
NAAA N-acylethanolamine acid amidase
NCKIPSD NCK interacting protein with SH3 domain
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFE2L3 nuclear factor, erythroid 2-like 3
NMT1 N-myristoyltransferase 1
NPR2 natriuretic peptide receptor 2
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PDGFB platelet-derived growth factor beta polypeptide
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLA2G3 phospholipase A2, group III
PLCH1 phospholipase C, eta 1
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRR5 proline rich 5 (renal)
PTRF polymerase I and transcript release factor
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
SCN1B sodium channel, voltage gated, type I beta subunit
SERHL2 serine hydrolase-like 2
SH3BP2 SH3-domain binding protein 2
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
STAG3 stromal antigen 3
TBXA2R thromboxane A2 receptor
THBS3 thrombospondin 3
TLE4 transducin-like enhancer of split 4
TM4SF4 transmembrane 4 L six family member 4
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNK1 tyrosine kinase, non-receptor, 1
TRPC1 transient receptor potential cation channel, subfamily C, member 1
UPK3B uroplakin 3B
USB1 U6 snRNA biogenesis 1
VIPR2 vasoactive intestinal peptide receptor 2
ZBTB22 zinc finger and BTB domain containing 22
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF675 zinc finger protein 675

decreased expression

Symbol Name
AGO3 argonaute RISC catalytic component 3
AKT1 v-akt murine thymoma viral oncogene homolog 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ATF7IP2 activating transcription factor 7 interacting protein 2
BCOR BCL6 corepressor
C11ORF80 chromosome 11 open reading frame 80
C17ORF75 chromosome 17 open reading frame 75
C17ORF80 chromosome 17 open reading frame 80
C6ORF47 chromosome 6 open reading frame 47
CCDC85C coiled-coil domain containing 85C
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLASP1 cytoplasmic linker associated protein 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DENND4C DENN/MADD domain containing 4C
DSN1 DSN1, MIS12 kinetochore complex component
DSPP dentin sialophosphoprotein
DUSP5 dual specificity phosphatase 5
F3 coagulation factor III (thromboplastin, tissue factor)
FAM184A family with sequence similarity 184, member A
FAM63A family with sequence similarity 63, member A
FLCN folliculin
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLS2 glutaminase 2 (liver, mitochondrial)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GTPBP2 GTP binding protein 2
HAUS6 HAUS augmin-like complex, subunit 6
HELZ helicase with zinc finger
HIST1H2AG histone cluster 1, H2ag
HIST1H2BC histone cluster 1, H2bc
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HP1BP3 heterochromatin protein 1, binding protein 3
IL15RA interleukin 15 receptor, alpha
INO80D INO80 complex subunit D
KIF14 kinesin family member 14
KIF18A kinesin family member 18A
LAMA3 laminin, alpha 3
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LOXL1 lysyl oxidase-like 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LY6D lymphocyte antigen 6 complex, locus D
MAP9 microtubule-associated protein 9
MFSD11 major facilitator superfamily domain containing 11
NBAS neuroblastoma amplified sequence
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
NUAK1 NUAK family, SNF1-like kinase, 1
P3H1 prolyl 3-hydroxylase 1
PACS1 phosphofurin acidic cluster sorting protein 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDGFRL platelet-derived growth factor receptor-like
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PMM1 phosphomannomutase 1
PNRC1 proline-rich nuclear receptor coactivator 1
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PYGB phosphorylase, glycogen; brain
RBL1 retinoblastoma-like 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RFTN1 raftlin, lipid raft linker 1
RHOBTB1 Rho-related BTB domain containing 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SECISBP2 SECIS binding protein 2
SECTM1 secreted and transmembrane 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SMA4 glucuronidase, beta pseudogene
SND1-IT1 SND1 intronic transcript 1
SPHK1 sphingosine kinase 1
STBD1 starch binding domain 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TCTN2 tectonic family member 2
THNSL1 threonine synthase-like 1 (S. cerevisiae)
THOP1 thimet oligopeptidase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM254 transmembrane protein 254
TNRC6B trinucleotide repeat containing 6B
TPST1 tyrosylprotein sulfotransferase 1
TRIM25 tripartite motif containing 25
UBXN6 UBX domain protein 6
VEGFC vascular endothelial growth factor C
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR7 WD repeat domain 7
WDR76 WD repeat domain 76
WLS wntless Wnt ligand secretion mediator
ZNF180 zinc finger protein 180
ZNF219 zinc finger protein 219
ZNF250 zinc finger protein 250
ZNF263 zinc finger protein 263
ZNF273 zinc finger protein 273
ZNF747 zinc finger protein 747
ZNF8 zinc finger protein 8
ZXDC ZXD family zinc finger C