determination Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Similar Terms
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Genes

447 genes co-occuring with the biological term determination in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ACVRL1 activin A receptor type II-like 1
ADA adenosine deaminase
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB2 adrenoceptor beta 2, surface
AFF1 AF4/FMR2 family, member 1
AFP alpha-fetoprotein
AGO2 argonaute RISC catalytic component 2
AGRN agrin
AGXT alanine-glyoxylate aminotransferase
AHSP alpha hemoglobin stabilizing protein
AIP aryl hydrocarbon receptor interacting protein
AKR1C4 aldo-keto reductase family 1, member C4
AKR1D1 aldo-keto reductase family 1, member D1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALOX5 arachidonate 5-lipoxygenase
AMH anti-Mullerian hormone
ANK1 ankyrin 1, erythrocytic
ANXA2 annexin A2
APLN apelin
APLNR apelin receptor
APOA5 apolipoprotein A-V
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
APRT adenine phosphoribosyltransferase
AQP7 aquaporin 7
AR androgen receptor
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ASXL1 additional sex combs like transcriptional regulator 1
ATM ATM serine/threonine kinase
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
AVP arginine vasopressin
AVPR1B arginine vasopressin receptor 1B
BAGE B melanoma antigen
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BCOR BCL6 corepressor
BIRC5 baculoviral IAP repeat containing 5
BMP2 bone morphogenetic protein 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1
BTD biotinidase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C3 complement component 3
C3AR1 complement component 3a receptor 1
C4A complement component 4A (Rodgers blood group)
C5AR1 complement component 5a receptor 1
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CALCA calcitonin-related polypeptide alpha
CALR calreticulin
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CCAR2 cell cycle and apoptosis regulator 2
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL26 chemokine (C-C motif) ligand 26
CCND1 cyclin D1
CCNE1 cyclin E1
CCNT1 cyclin T1
CD109 CD109 molecule
CD14 CD14 molecule
CD164 CD164 molecule, sialomucin
CD27 CD27 molecule
CD34 CD34 molecule
CD38 CD38 molecule
CD4 CD4 molecule
CD44 CD44 molecule (Indian blood group)
CD82 CD82 molecule
CDC42 cell division cycle 42
CDCA4 cell division cycle associated 4
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CEL carboxyl ester lipase
CELF2 CUGBP, Elav-like family member 2
CELF4 CUGBP, Elav-like family member 4
CER1 cerberus 1, DAN family BMP antagonist
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGA glycoprotein hormones, alpha polypeptide
CHEK2 checkpoint kinase 2
CHGA chromogranin A
CHIT1 chitinase 1 (chitotriosidase)
CHM choroideremia (Rab escort protein 1)
CKBE creatine kinase, ectopic expression
CLSPN claspin
COL1A1 collagen, type I, alpha 1
CP ceruloplasmin (ferroxidase)
CPEB3 cytoplasmic polyadenylation element binding protein 3
CRP C-reactive protein, pentraxin-related
CSF3R colony stimulating factor 3 receptor (granulocyte)
CST3 cystatin C
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTPS1 CTP synthase 1
CTPS2 CTP synthase 2
CTSB cathepsin B
CTSD cathepsin D
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DACH1 dachshund family transcription factor 1
DBT dihydrolipoamide branched chain transacylase E2
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DKC1 dyskeratosis congenita 1, dyskerin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLG4 discs, large homolog 4 (Drosophila)
DMD dystrophin
DPY30 dpy-30 homolog (C. elegans)
DUSP27 dual specificity phosphatase 27 (putative)
E2F2 E2F transcription factor 2
E2F3 E2F transcription factor 3
ECI1 enoyl-CoA delta isomerase 1
EDN1 endothelin 1
EDNRB endothelin receptor type B
EGFR epidermal growth factor receptor
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF5B eukaryotic translation initiation factor 5B
ELANE elastase, neutrophil expressed
ENG endoglin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC1 excision repair cross-complementation group 1
ESR1 estrogen receptor 1
ESRRG estrogen-related receptor gamma
F10 coagulation factor X
F3 coagulation factor III (thromboplastin, tissue factor)
F8 coagulation factor VIII, procoagulant component
F9 coagulation factor IX
FANCA Fanconi anemia, complementation group A
FASLG Fas ligand (TNF superfamily, member 6)
FEN1 flap structure-specific endonuclease 1
FGA fibrinogen alpha chain
FGF2 fibroblast growth factor 2 (basic)
FGF9 fibroblast growth factor 9
FGFR4 fibroblast growth factor receptor 4
FLT3 fms-related tyrosine kinase 3
FN1 fibronectin 1
FOXC1 forkhead box C1
FOXM1 forkhead box M1
FOXP1 forkhead box P1
FOXP3 forkhead box P3
FSHB follicle stimulating hormone, beta polypeptide
FXYD1 FXYD domain containing ion transport regulator 1
FXYD3 FXYD domain containing ion transport regulator 3
FXYD4 FXYD domain containing ion transport regulator 4
G6PD glucose-6-phosphate dehydrogenase
GAGE1 G antigen 1
GCG glucagon
GCH1 GTP cyclohydrolase 1
GFAP glial fibrillary acidic protein
GH1 growth hormone 1
GHR growth hormone receptor
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GJA3 gap junction protein, alpha 3, 46kDa
GJA4 gap junction protein, alpha 4, 37kDa
GLP1R glucagon-like peptide 1 receptor
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPX3 glutathione peroxidase 3
GREM1 gremlin 1, DAN family BMP antagonist
GRHL2 grainyhead-like 2 (Drosophila)
GRP gastrin-releasing peptide
GSTP1 glutathione S-transferase pi 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HAMP hepcidin antimicrobial peptide
HBB hemoglobin, beta
HDAC1 histone deacetylase 1
HEXIM1 hexamethylene bis-acetamide inducible 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HMOX1 heme oxygenase 1
HP haptoglobin
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSPA1B heat shock 70kDa protein 1B
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IDE insulin-degrading enzyme
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFNL3 interferon, lambda 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFBP1 insulin-like growth factor binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
IGHMBP2 immunoglobulin mu binding protein 2
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL18 interleukin 18
IL1B interleukin 1, beta
IL4 interleukin 4
IL6 interleukin 6
IL6R interleukin 6 receptor
INHBA inhibin, beta A
INHBB inhibin, beta B
IRF4 interferon regulatory factor 4
ITGA1 integrin, alpha 1
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK2 Janus kinase 2
JUN jun proto-oncogene
KAT8 K(lysine) acetyltransferase 8
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIF11 kinesin family member 11
KIF3A kinesin family member 3A
KIF5A kinesin family member 5A
KIN Kin17 DNA and RNA binding protein
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KLF4 Kruppel-like factor 4 (gut)
KLKB1 kallikrein B, plasma (Fletcher factor) 1
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
L3MBTL2 l(3)mbt-like 2 (Drosophila)
LAMP1 lysosomal-associated membrane protein 1
LEF1 lymphoid enhancer-binding factor 1
LEP leptin
LETMD1 LETM1 domain containing 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS4 lectin, galactoside-binding, soluble, 4
LMNA lamin A/C
LYPLA1 lysophospholipase I
MAGEA1 melanoma antigen family A1
MAGEA3 melanoma antigen family A3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MB myoglobin
MBD1 methyl-CpG binding domain protein 1
MBL2 mannose-binding lectin (protein C) 2, soluble
MBP myelin basic protein
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MEF2C myocyte enhancer factor 2C
MEN1 multiple endocrine neoplasia I
MGMT O-6-methylguanine-DNA methyltransferase
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MIR137 microRNA 137
MIR21 microRNA 21
MIRLET7G microRNA let-7g
MKI67 marker of proliferation Ki-67
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
MME membrane metallo-endopeptidase
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MORC3 MORC family CW-type zinc finger 3
MPO myeloperoxidase
MTA3 metastasis associated 1 family, member 3
MTDH metadherin
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC1 mucin 1, cell surface associated
MVP major vault protein
MX1 MX dynamin-like GTPase 1
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYOD1 myogenic differentiation 1
NAGS N-acetylglutamate synthase
NAMPT nicotinamide phosphoribosyltransferase
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NEFH neurofilament, heavy polypeptide
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NGB neuroglobin
NKX2-2 NK2 homeobox 2
NMNAT1 nicotinamide nucleotide adenylyltransferase 1
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPPB natriuretic peptide B
NPY4R neuropeptide Y receptor Y4
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRL neural retina leucine zipper
NUTM1 NUT midline carcinoma, family member 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PADI6 peptidyl arginine deiminase, type VI
PAEP progestagen-associated endometrial protein
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAH phenylalanine hydroxylase
PARP1 poly (ADP-ribose) polymerase 1
PARP2 poly (ADP-ribose) polymerase 2
PARP9 poly (ADP-ribose) polymerase family, member 9
PAX5 paired box 5
PAX6 paired box 6
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PDGFB platelet-derived growth factor beta polypeptide
PDGFC platelet derived growth factor C
PDHX pyruvate dehydrogenase complex, component X
PGR progesterone receptor
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIBF1 progesterone immunomodulatory binding factor 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PITX3 paired-like homeodomain 3
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAGL1 pleiomorphic adenoma gene-like 1
PLAU plasminogen activator, urokinase
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PON1 paraoxonase 1
PPAP2A phosphatidic acid phosphatase type 2A
PPARG peroxisome proliferator-activated receptor gamma
PPP5C protein phosphatase 5, catalytic subunit
PREP prolyl endopeptidase
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PROX1 prospero homeobox 1
PRTN3 proteinase 3
PSAP prosaposin
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTTG1 pituitary tumor-transforming 1
RAB27A RAB27A, member RAS oncogene family
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RENBP renin binding protein
RET ret proto-oncogene
RHCE Rh blood group, CcEe antigens
RHD Rh blood group, D antigen
RHOA ras homolog family member A
RHOB ras homolog family member B
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RSPO1 R-spondin 1
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
RUNX2 runt-related transcription factor 2
S100B S100 calcium binding protein B
SATB1 SATB homeobox 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFN stratifin
SGMS2 sphingomyelin synthase 2
SHH sonic hedgehog
SIRT1 sirtuin 1
SLC17A3 solute carrier family 17 (organic anion transporter), member 3
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLC38A1 solute carrier family 38, member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMOC2 SPARC related modular calcium binding 2
SOD2 superoxide dismutase 2, mitochondrial
SOX1 SRY (sex determining region Y)-box 1
SOX11 SRY (sex determining region Y)-box 11
SOX9 SRY (sex determining region Y)-box 9
SRY sex determining region Y
SSTR2 somatostatin receptor 2
SSTR3 somatostatin receptor 3
SSTR5 somatostatin receptor 5
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SULT4A1 sulfotransferase family 4A, member 1
TANK TRAF family member-associated NFKB activator
TARDBP TAR DNA binding protein
TAS1R1 taste receptor, type 1, member 1
TAS1R3 taste receptor, type 1, member 3
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TET2 tet methylcytosine dioxygenase 2
TF transferrin
TFF1 trefoil factor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFB3 transforming growth factor, beta 3
TGFBR3 transforming growth factor, beta receptor III
THBD thrombomodulin
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNNI3 troponin I type 3 (cardiac)
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1
TPH2 tryptophan hydroxylase 2
TRIM50 tripartite motif containing 50
TUBB3 tubulin, beta 3 class III
TWIST1 twist family bHLH transcription factor 1
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGT1A UDP glucuronosyltransferase 1 family, polypeptide A complex locus
UMPS uridine monophosphate synthetase
VASP vasodilator-stimulated phosphoprotein
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VKORC1 vitamin K epoxide reductase complex, subunit 1
VSIG4 V-set and immunoglobulin domain containing 4
VWF von Willebrand factor
WDR5 WD repeat domain 5
WFDC2 WAP four-disulfide core domain 2
WNK1 WNK lysine deficient protein kinase 1
WNT16 wingless-type MMTV integration site family, member 16
WNT5A wingless-type MMTV integration site family, member 5A
WNT7A wingless-type MMTV integration site family, member 7A
WT1 Wilms tumor 1
XBP1 X-box binding protein 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YBX1 Y box binding protein 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZFP42 ZFP42 zinc finger protein