dequalinium chloride-2631 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the dequalinium chloride-2631 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AIF1 allograft inflammatory factor 1
ALCAM activated leukocyte cell adhesion molecule
ALDOB aldolase B, fructose-bisphosphate
ARHGAP25 Rho GTPase activating protein 25
ARHGAP26 Rho GTPase activating protein 26
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BBC3 BCL2 binding component 3
BTF3P11 basic transcription factor 3 pseudogene 11
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CORO7 coronin 7
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DLX2 distal-less homeobox 2
DST dystonin
DVL3 dishevelled segment polarity protein 3
EFR3B EFR3 homolog B (S. cerevisiae)
ETV4 ets variant 4
FGF20 fibroblast growth factor 20
FXR2 fragile X mental retardation, autosomal homolog 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GFI1 growth factor independent 1 transcription repressor
GLG1 golgi glycoprotein 1
GLP1R glucagon-like peptide 1 receptor
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
HDAC5 histone deacetylase 5
HMOX1 heme oxygenase 1
HOXC8 homeobox C8
HOXD1 homeobox D1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL1R2 interleukin 1 receptor, type II
INHBE inhibin, beta E
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
JADE2 jade family PHD finger 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF25-AS1 KIF25 antisense RNA 1
LDHB lactate dehydrogenase B
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MARK4 MAP/microtubule affinity-regulating kinase 4
MED6 mediator complex subunit 6
MTCP1 mature T-cell proliferation 1
MUC3B mucin 3B, cell surface associated
MYEF2 myelin expression factor 2
NUPR1 nuclear protein, transcriptional regulator, 1
OCA2 oculocutaneous albinism II
OLFML2B olfactomedin-like 2B
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OVOL2 ovo-like zinc finger 2
PCDH12 protocadherin 12
PCDH17 protocadherin 17
PCM1 pericentriolar material 1
PDE9A phosphodiesterase 9A
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPARG peroxisome proliferator-activated receptor gamma
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PTAFR platelet-activating factor receptor
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPRS protein tyrosine phosphatase, receptor type, S
RABGAP1 RAB GTPase activating protein 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBFA ribosome binding factor A (putative)
RBM19 RNA binding motif protein 19
RHEB Ras homolog enriched in brain
RTN2 reticulon 2
RUNX1 runt-related transcription factor 1
RUSC2 RUN and SH3 domain containing 2
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SIK3 SIK family kinase 3
SIX6 SIX homeobox 6
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC17A2 solute carrier family 17, member 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A30 solute carrier family 25, member 30
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPTAN1 spectrin, alpha, non-erythrocytic 1
TAZ tafazzin
TBX6 T-box 6
TFEB transcription factor EB
TP53I11 tumor protein p53 inducible protein 11
TUBG2 tubulin, gamma 2
UPK3B uroplakin 3B
VEGFA vascular endothelial growth factor A
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR59 WD repeat domain 59
WSB1 WD repeat and SOCS box containing 1
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADGRA3 adhesion G protein-coupled receptor A3
ANKRD40 ankyrin repeat domain 40
ASB6 ankyrin repeat and SOCS box containing 6
ASB9 ankyrin repeat and SOCS box containing 9
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD3A ATPase family, AAA domain containing 3A
BBS10 Bardet-Biedl syndrome 10
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BTD biotinidase
C11ORF30 chromosome 11 open reading frame 30
C17ORF80 chromosome 17 open reading frame 80
C1ORF115 chromosome 1 open reading frame 115
C21ORF91 chromosome 21 open reading frame 91
C22ORF46 chromosome 22 open reading frame 46
C5AR2 complement component 5a receptor 2
CCDC88C coiled-coil domain containing 88C
CCDC9 coiled-coil domain containing 9
CCNJ cyclin J
CD79B CD79b molecule, immunoglobulin-associated beta
CENPQ centromere protein Q
CLDND1 claudin domain containing 1
CLSPN claspin
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EFHD2 EF-hand domain family, member D2
EGLN3 egl-9 family hypoxia-inducible factor 3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERCC4 excision repair cross-complementation group 4
ETAA1 Ewing tumor-associated antigen 1
EXOC5 exocyst complex component 5
FKBP5 FK506 binding protein 5
FLJ10038 uncharacterized protein FLJ10038
FLRT3 fibronectin leucine rich transmembrane protein 3
FMO4 flavin containing monooxygenase 4
FYCO1 FYVE and coiled-coil domain containing 1
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GNA13 guanine nucleotide binding protein (G protein), alpha 13
HLA-J major histocompatibility complex, class I, J (pseudogene)
HSPA2 heat shock 70kDa protein 2
IFT81 intraflagellar transport 81
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
LAMA3 laminin, alpha 3
LIN7A lin-7 homolog A (C. elegans)
LOC100287590 uncharacterized LOC100287590
LRRC8E leucine rich repeat containing 8 family, member E
MAGEH1 melanoma antigen family H1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MCM10 minichromosome maintenance complex component 10
MSMB microseminoprotein, beta-
MTERF1 mitochondrial transcription termination factor 1
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NUPL2 nucleoporin like 2
ODF2 outer dense fiber of sperm tails 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PISD phosphatidylserine decarboxylase
PMP22 peripheral myelin protein 22
PODXL2 podocalyxin-like 2
PPT2 palmitoyl-protein thioesterase 2
PRICKLE3 prickle homolog 3 (Drosophila)
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB23 RAB23, member RAS oncogene family
RGS19 regulator of G-protein signaling 19
RIBC2 RIB43A domain with coiled-coils 2
RPUSD2 RNA pseudouridylate synthase domain containing 2
S100A4 S100 calcium binding protein A4
SCD5 stearoyl-CoA desaturase 5
SCYL2 SCY1-like 2 (S. cerevisiae)
SETMAR SET domain and mariner transposase fusion gene
SFT2D2 SFT2 domain containing 2
SGK1 serum/glucocorticoid regulated kinase 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNIP1 Smad nuclear interacting protein 1
STK16 serine/threonine kinase 16
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBCC tubulin folding cofactor C
TEAD3 TEA domain family member 3
THOP1 thimet oligopeptidase 1
TMEM110 transmembrane protein 110
TMPRSS3 transmembrane protease, serine 3
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TTC23 tetratricopeptide repeat domain 23
USP18 ubiquitin specific peptidase 18
USP20 ubiquitin specific peptidase 20
VWA1 von Willebrand factor A domain containing 1
XAB2 XPA binding protein 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZCCHC2 zinc finger, CCHC domain containing 2
ZNF446 zinc finger protein 446
ZNF562 zinc finger protein 562
ZNF573 zinc finger protein 573
ZNHIT2 zinc finger, HIT-type containing 2