dequalinium chloride-1276 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the dequalinium chloride-1276 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAM28 ADAM metallopeptidase domain 28
ALX3 ALX homeobox 3
APOL2 apolipoprotein L, 2
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARMC7 armadillo repeat containing 7
BAD BCL2-associated agonist of cell death
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BTBD2 BTB (POZ) domain containing 2
CCND1 cyclin D1
CCNT2 cyclin T2
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD47 CD47 molecule
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CIZ1 CDKN1A interacting zinc finger protein 1
CLCN7 chloride channel, voltage-sensitive 7
CLEC4A C-type lectin domain family 4, member A
CNGB3 cyclic nucleotide gated channel beta 3
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
COX4I1 cytochrome c oxidase subunit IV isoform 1
CSE1L CSE1 chromosome segregation 1-like (yeast)
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DCAF15 DDB1 and CUL4 associated factor 15
DGAT1 diacylglycerol O-acyltransferase 1
DST dystonin
EIF5 eukaryotic translation initiation factor 5
FRY furry homolog (Drosophila)
GLG1 golgi glycoprotein 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNS glucosamine (N-acetyl)-6-sulfatase
HEXIM1 hexamethylene bis-acetamide inducible 1
HIST1H2BI histone cluster 1, H2bi
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
IQCE IQ motif containing E
KANK1 KN motif and ankyrin repeat domains 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KYNU kynureninase
LIG3 ligase III, DNA, ATP-dependent
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LTC4S leukotriene C4 synthase
MAPK3 mitogen-activated protein kinase 3
MAST3 microtubule associated serine/threonine kinase 3
MDC1 mediator of DNA-damage checkpoint 1
MEF2D myocyte enhancer factor 2D
MIIP migration and invasion inhibitory protein
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MTRF1L mitochondrial translational release factor 1-like
NEB nebulin
NF2 neurofibromin 2 (merlin)
NNAT neuronatin
NRP1 neuropilin 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PBX2 pre-B-cell leukemia homeobox 2
PDE4B phosphodiesterase 4B, cAMP-specific
PEX10 peroxisomal biogenesis factor 10
PEX6 peroxisomal biogenesis factor 6
PHC1 polyhomeotic homolog 1 (Drosophila)
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PSD4 pleckstrin and Sec7 domain containing 4
PTTG1 pituitary tumor-transforming 1
PWAR5 Prader Willi/Angelman region RNA 5
PYGB phosphorylase, glycogen; brain
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RABGAP1L RAB GTPase activating protein 1-like
RNF126P1 ring finger protein 126 pseudogene 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SEC14L1 SEC14-like 1 (S. cerevisiae)
SEC23A Sec23 homolog A (S. cerevisiae)
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMAD3 SMAD family member 3
SMG7 SMG7 nonsense mediated mRNA decay factor
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TAS2R10 taste receptor, type 2, member 10
THOC5 THO complex 5
TMCC1 transmembrane and coiled-coil domain family 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TOP3A topoisomerase (DNA) III alpha
TPD52L1 tumor protein D52-like 1
TRABD TraB domain containing
VCAN versican
VPRBP Vpr (HIV-1) binding protein
WDR91 WD repeat domain 91
WDTC1 WD and tetratricopeptide repeats 1
ZNF226 zinc finger protein 226
ZNF473 zinc finger protein 473
ZNF552 zinc finger protein 552
ZNF667 zinc finger protein 667

decreased expression

Symbol Name
ADM adrenomedullin
ALDOC aldolase C, fructose-bisphosphate
ARG1 arginase 1
ATF3 activating transcription factor 3
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C1ORF21 chromosome 1 open reading frame 21
C3 complement component 3
CCDC47 coiled-coil domain containing 47
CCNE2 cyclin E2
CCRL2 chemokine (C-C motif) receptor-like 2
CD69 CD69 molecule
CD83 CD83 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFP complement factor properdin
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHKB choline kinase beta
CHST10 carbohydrate sulfotransferase 10
CLEC7A C-type lectin domain family 7, member A
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CPNE1 copine I
CYTIP cytohesin 1 interacting protein
DAAM1 dishevelled associated activator of morphogenesis 1
DDIT4 DNA-damage-inducible transcript 4
DUSP5 dual specificity phosphatase 5
EGR1 early growth response 1
EGR2 early growth response 2
ENO2 enolase 2 (gamma, neuronal)
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FICD FIC domain containing
FILIP1L filamin A interacting protein 1-like
GCA grancalcin, EF-hand calcium binding protein
GPRC5C G protein-coupled receptor, class C, group 5, member C
HAUS6 HAUS augmin-like complex, subunit 6
HCAR3 hydroxycarboxylic acid receptor 3
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HILPDA hypoxia inducible lipid droplet-associated
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HP haptoglobin
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HSPA13 heat shock protein 70kDa family, member 13
IDI1 isopentenyl-diphosphate delta isomerase 1
IL1B interleukin 1, beta
INSIG1 insulin induced gene 1
JUN jun proto-oncogene
KAT2A K(lysine) acetyltransferase 2A
KDM3A lysine (K)-specific demethylase 3A
KLF10 Kruppel-like factor 10
KLHL12 kelch-like family member 12
LINC00339 long intergenic non-protein coding RNA 339
LMNB1 lamin B1
MBD5 methyl-CpG binding domain protein 5
MKNK2 MAP kinase interacting serine/threonine kinase 2
MRPL52 mitochondrial ribosomal protein L52
MSMO1 methylsterol monooxygenase 1
NARF nuclear prelamin A recognition factor
NCF1C neutrophil cytosolic factor 1C pseudogene
NDRG1 N-myc downstream regulated 1
NEU1 sialidase 1 (lysosomal sialidase)
NFIL3 nuclear factor, interleukin 3 regulated
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PFKP phosphofructokinase, platelet
PHC2 polyhomeotic homolog 2 (Drosophila)
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB8B RAB8B, member RAS oncogene family
RGCC regulator of cell cycle
RGS13 regulator of G-protein signaling 13
RGS16 regulator of G-protein signaling 16
RGS2 regulator of G-protein signaling 2
RHOBTB2 Rho-related BTB domain containing 2
RLF rearranged L-myc fusion
RNF187 ring finger protein 187
RRAGA Ras-related GTP binding A
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPP1 secreted phosphoprotein 1
SREK1IP1 SREK1-interacting protein 1
STK25 serine/threonine kinase 25
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM45A transmembrane protein 45A
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TREM1 triggering receptor expressed on myeloid cells 1
TRIB1 tribbles pseudokinase 1
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TUBB6 tubulin, beta 6 class V
TXNIP thioredoxin interacting protein
USP11 ubiquitin specific peptidase 11
VGLL4 vestigial-like family member 4
XPC xeroderma pigmentosum, complementation group C
ZCCHC2 zinc finger, CCHC domain containing 2
ZNF14 zinc finger protein 14
ZNF395 zinc finger protein 395
ZNF654 zinc finger protein 654