dental malocclusion Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description Dental malocclusion refers to an abnormality of the occlusion, or alignment, of the teeth and the way the upper and lower teeth fit together, resulting in overcrowding of teeth or in abnormal bite patterns. (Human Phenotype Ontology, HP_0000689)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0000689
Similar Terms
Downloads & Tools

Genes

81 genes associated with the dental malocclusion phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
AMER1 APC membrane recruitment protein 1
ASPH aspartate beta-hydroxylase
ATR ATR serine/threonine kinase
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCOR BCL6 corepressor
BRAF B-Raf proto-oncogene, serine/threonine kinase
CA2 carbonic anhydrase II
CHD7 chromodomain helicase DNA binding protein 7
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLIP2 CAP-GLY domain containing linker protein 2
CREBBP CREB binding protein
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCHS1 dachsous cadherin-related 1
ELN elastin
ENAM enamelin
EP300 E1A binding protein p300
ERCC6 excision repair cross-complementation group 6
ERCC8 excision repair cross-complementation group 8
FAM83H family with sequence similarity 83, member H
FAT4 FAT atypical cadherin 4
FERMT1 fermitin family member 1
FGF3 fibroblast growth factor 3
FGFR2 fibroblast growth factor receptor 2
FLNA filamin A, alpha
FOXC1 forkhead box C1
FRAS1 Fraser extracellular matrix complex subunit 1
FREM2 FRAS1 related extracellular matrix protein 2
GLI2 GLI family zinc finger 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAS GNAS complex locus
GPC3 glypican 3
GRIP1 glutamate receptor interacting protein 1
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
HDAC9 histone deacetylase 9
IRX5 iroquois homeobox 5
KDM6A lysine (K)-specific demethylase 6A
LIMK1 LIM domain kinase 1
LRP5 low density lipoprotein receptor-related protein 5
MUSK muscle, skeletal, receptor tyrosine kinase
NOTCH2 notch 2
OCRL oculocerebrorenal syndrome of Lowe
OFD1 oral-facial-digital syndrome 1
PAX1 paired box 1
PAX6 paired box 6
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDE4D phosphodiesterase 4D, cAMP-specific
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PITX2 paired-like homeodomain 2
PLCB4 phospholipase C, beta 4
POLR1C polymerase (RNA) I polypeptide C, 30kDa
POLR1D polymerase (RNA) I polypeptide D, 16kDa
PORCN porcupine homolog (Drosophila)
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAB40AL RAB40A, member RAS oncogene family-like
RAI1 retinoic acid induced 1
RAPSN receptor-associated protein of the synapse
RFC2 replication factor C (activator 1) 2, 40kDa
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RUNX2 runt-related transcription factor 2
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SH3PXD2B SH3 and PX domains 2B
SHANK3 SH3 and multiple ankyrin repeat domains 3
SKI SKI proto-oncogene
SLC39A13 solute carrier family 39 (zinc transporter), member 13
SMAD3 SMAD family member 3
SOS1 son of sevenless homolog 1 (Drosophila)
SOST sclerostin
TBL2 transducin (beta)-like 2
TCOF1 Treacher Collins-Franceschetti syndrome 1
TGFB2 transforming growth factor, beta 2
THOC6 THO complex 6
TRPS1 trichorhinophalangeal syndrome I
UBB ubiquitin B
WNT10A wingless-type MMTV integration site family, member 10A
WNT5A wingless-type MMTV integration site family, member 5A