degenerative arthropathy ; osteoarthritis Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group metabolic (Genetic Association Database)
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Genes

37 genes associated with the disease degenerative arthropathy ; osteoarthritis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
COL1A1 collagen, type I, alpha 1
CRP C-reactive protein, pentraxin-related
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DIO2 deiodinase, iodothyronine, type II
DIO3 deiodinase, iodothyronine, type III
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FRZB frizzled-related protein
GDF5 growth differentiation factor 5
GPX1 glutathione peroxidase 1
HFE hemochromatosis
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IHH indian hedgehog
IL10 interleukin 10
IL13 interleukin 13
IL18R1 interleukin 18 receptor 1
IL18RAP interleukin 18 receptor accessory protein
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
IL1RL1 interleukin 1 receptor-like 1
IL1RL2 interleukin 1 receptor-like 2
IL1RN interleukin 1 receptor antagonist
IL4 interleukin 4
IL4R interleukin 4 receptor
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MATN3 matrilin 3
NME8 NME/NM23 family member 8
RHOB ras homolog family member B
SEPP1 selenoprotein P, plasma, 1
SOCS1 suppressor of cytokine signaling 1
THRA thyroid hormone receptor, alpha
TXNRD2 thioredoxin reductase 2
USP33 ubiquitin specific peptidase 33
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor