decreased vasodilation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less than the expected or normal widening of the lumen of the blood vessels (Mammalian Phenotype Ontology, MP_0005591)
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27 gene mutations causing the decreased vasodilation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOE apolipoprotein E
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASL argininosuccinate lyase
CHRM3 cholinergic receptor, muscarinic 3
CTH cystathionine gamma-lyase
EDNRB endothelin receptor type B
IER3 immediate early response 3
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLK3 kallikrein-related peptidase 3
NOS3 nitric oxide synthase 3 (endothelial cell)
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDC phosducin
PECAM1 platelet/endothelial cell adhesion molecule 1
PRKG1 protein kinase, cGMP-dependent, type I
PTGDR prostaglandin D2 receptor (DP)
PTK2B protein tyrosine kinase 2 beta
PTPRM protein tyrosine phosphatase, receptor type, M
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RGS2 regulator of G-protein signaling 2
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SMAD6 SMAD family member 6
TIMP3 TIMP metallopeptidase inhibitor 3
TRPC4 transient receptor potential cation channel, subfamily C, member 4