decreased vasoconstriction Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced ability to constrict the nonstriated, involuntary muscle tissue of the blood vessels (Mammalian Phenotype Ontology, MP_0003026)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003026
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Genes

17 gene mutations causing the decreased vasoconstriction phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ADRA1A adrenoceptor alpha 1A
ADRA1B adrenoceptor alpha 1B
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ASIC2 acid sensing (proton gated) ion channel 2
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
CAV1 caveolin 1, caveolae protein, 22kDa
FGF2 fibroblast growth factor 2 (basic)
IL10 interleukin 10
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
MYH11 myosin, heavy chain 11, smooth muscle
NCF1 neutrophil cytosolic factor 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
REN renin
SMTN smoothelin
SMTNL1 smoothelin-like 1