decreased tumor growth/size Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less than expected development of tumorous growth when compared to controls (Mammalian Phenotype Ontology, MP_0003447)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003447
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Genes

48 gene mutations causing the decreased tumor growth/size phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADAM15 ADAM metallopeptidase domain 15
ANTXR1 anthrax toxin receptor 1
ANXA1 annexin A1
APC adenomatous polyposis coli
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
CCM2L cerebral cavernous malformation 2-like
CCR2 chemokine (C-C motif) receptor 2
CD248 CD248 molecule, endosialin
CD44 CD44 molecule (Indian blood group)
CXCR2 chemokine (C-X-C motif) receptor 2
CYBB cytochrome b-245, beta polypeptide
DOT1L DOT1-like histone H3K79 methyltransferase
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FBLN5 fibulin 5
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GPR68 G protein-coupled receptor 68
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
H2AFX H2A histone family, member X
HCST hematopoietic cell signal transducer
HPRT1 hypoxanthine phosphoribosyltransferase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IL12RB2 interleukin 12 receptor, beta 2
IL1B interleukin 1, beta
IL6R interleukin 6 receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MSI2 musashi RNA-binding protein 2
MUC1 mucin 1, cell surface associated
NRP1 neuropilin 1
PDCD1 programmed cell death 1
PGF placental growth factor
PLAU plasminogen activator, urokinase
PLD1 phospholipase D1, phosphatidylcholine-specific
PLG plasminogen
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RALGDS ral guanine nucleotide dissociation stimulator
SKIL SKI-like proto-oncogene
STAG1 stromal antigen 1
TP53 tumor protein p53
TRIM27 tripartite motif containing 27