decreased trophoblast giant cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description fewer than normal number of cells of the extraembryonic cell layer that contributes to the placenta (Mammalian Phenotype Ontology, MP_0001713)
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36 gene mutations causing the decreased trophoblast giant cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
AURKB aurora kinase B
BIRC5 baculoviral IAP repeat containing 5
BRCA1 breast cancer 1, early onset
CDX2 caudal type homeobox 2
COPS2 COP9 signalosome subunit 2
CUL7 cullin 7
DNM1L dynamin 1-like
EGFR epidermal growth factor receptor
EGLN1 egl-9 family hypoxia-inducible factor 1
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ELAVL1 ELAV like RNA binding protein 1
EOMES eomesodermin
EPCAM epithelial cell adhesion molecule
ESRRB estrogen-related receptor beta
FEN1 flap structure-specific endonuclease 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAB1 GRB2-associated binding protein 1
HAND1 heart and neural crest derivatives expressed 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
IL11RA interleukin 11 receptor, alpha
MAPK14 mitogen-activated protein kinase 14
MDFI MyoD family inhibitor
MET MET proto-oncogene, receptor tyrosine kinase
MFN2 mitofusin 2
PNPLA6 patatin-like phospholipase domain containing 6
PRDM1 PR domain containing 1, with ZNF domain
RTEL1 regulator of telomere elongation helicase 1
RYBP RING1 and YY1 binding protein
SALL4 spalt-like transcription factor 4
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
TEAD4 TEA domain family member 4
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFDP1 transcription factor Dp-1
THBD thrombomodulin
TTPA tocopherol (alpha) transfer protein