decreased transitional stage t2 b cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced number of a type of transitional stage B cell that has the phenotype surface IgM-positive, surface IgD-postive, CD21-positive, CD23-positive, CD62L-negative, and is located in the splenic B follicles (Mammalian Phenotype Ontology, MP_0009926)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009926
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Genes

10 gene mutations causing the decreased transitional stage t2 b cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AKAP13 A kinase (PRKA) anchor protein 13
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATP11C ATPase, class VI, type 11C
BCL3 B-cell CLL/lymphoma 3
CD22 CD22 molecule
HAX1 HCLS1 associated protein X-1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
SPPL2A signal peptide peptidase like 2A
SYK spleen tyrosine kinase