decreased transitional stage b cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced number of immature B cells of an intermediate stage between the pre-B cell stage and the mature naive stage; transitional B cells express surface immunoglobulin, and are subject to the process of B cell selection (Mammalian Phenotype Ontology, MP_0008190)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008190
Similar Terms
Downloads & Tools

Genes

30 gene mutations causing the decreased transitional stage b cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AKAP13 A kinase (PRKA) anchor protein 13
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATP11C ATPase, class VI, type 11C
BCL3 B-cell CLL/lymphoma 3
BLNK B-cell linker
BTK Bruton agammaglobulinemia tyrosine kinase
CD22 CD22 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FAS Fas cell surface death receptor
FNIP1 folliculin interacting protein 1
HAX1 HCLS1 associated protein X-1
IGHM immunoglobulin heavy constant mu
LTA lymphotoxin alpha
LYN LYN proto-oncogene, Src family tyrosine kinase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NPY1R neuropeptide Y receptor Y1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
SH2D1A SH2 domain containing 1A
SH3BP2 SH3-domain binding protein 2
SPNS2 spinster homolog 2 (Drosophila)
SPPL2A signal peptide peptidase like 2A
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SYK spleen tyrosine kinase
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
ZBTB1 zinc finger and BTB domain containing 1