decreased thymocyte apoptosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the number of immature T cells located in the thymus that are undergoing programmed cell death (Mammalian Phenotype Ontology, MP_0009542)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009542
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Genes

13 gene mutations causing the decreased thymocyte apoptosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CD247 CD247 molecule
CDK6 cyclin-dependent kinase 6
DTX1 deltex 1, E3 ubiquitin ligase
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
KLF13 Kruppel-like factor 13
LCN2 lipocalin 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
NDRG1 N-myc downstream regulated 1
PERP PERP, TP53 apoptosis effector
PRKDC protein kinase, DNA-activated, catalytic polypeptide
TMEM109 transmembrane protein 109
TP53 tumor protein p53