decreased thermal nociceptive threshold Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description a lower than average point at which thermal pain sensation is first detectable (Mammalian Phenotype Ontology, MP_0003998)
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42 gene mutations causing the decreased thermal nociceptive threshold phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACPP acid phosphatase, prostate
ADGRG1 adhesion G protein-coupled receptor G1
ADORA1 adenosine A1 receptor
AFF2 AF4/FMR2 family, member 2
ARX aristaless related homeobox
ASIC3 acid sensing (proton gated) ion channel 3
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BACE1 beta-site APP-cleaving enzyme 1
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CNTNAP2 contactin associated protein-like 2
FABP3 fatty acid binding protein 3, muscle and heart
FBXO11 F-box protein 11
FRMPD4 FERM and PDZ domain containing 4
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GRK5 G protein-coupled receptor kinase 5
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
LMO7 LIM domain 7
MMP24 matrix metallopeptidase 24 (membrane-inserted)
NDN necdin, melanoma antigen (MAGE) family member
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
PDE8A phosphodiesterase 8A
PITX3 paired-like homeodomain 3
PPARD peroxisome proliferator-activated receptor delta
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PRX periaxin
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3
SCN10A sodium channel, voltage gated, type X alpha subunit
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
SHANK3 SH3 and multiple ankyrin repeat domains 3
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SMN1 survival of motor neuron 1, telomeric
TLR2 toll-like receptor 2
TPCN2 two pore segment channel 2