decreased testis weight Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced average weight of the male reproductive glands (Mammalian Phenotype Ontology, MP_0004852)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004852
Similar Terms
Downloads & Tools

Genes

201 gene mutations causing the decreased testis weight phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACVR2A activin A receptor, type IIA
ADIPOR2 adiponectin receptor 2
ADRA1B adrenoceptor alpha 1B
AGO4 argonaute RISC catalytic component 4
AHR aryl hydrocarbon receptor
AKAP9 A kinase (PRKA) anchor protein 9
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ALKBH5 AlkB family member 5, RNA demethylase
AR androgen receptor
ARL4A ADP-ribosylation factor-like 4A
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1
ATAT1 alpha tubulin acetyltransferase 1
ATR ATR serine/threonine kinase
BAX BCL2-associated X protein
BCL2L2 BCL2-like 2
BCO2 beta-carotene oxygenase 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP8B bone morphogenetic protein 8b
BOLL boule-like RNA-binding protein
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CADM1 cell adhesion molecule 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCNA1 cyclin A1
CCND2 cyclin D2
CDK4 cyclin-dependent kinase 4
CDKN2A cyclin-dependent kinase inhibitor 2A
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
CIB1 calcium and integrin binding 1 (calmyrin)
CNBD2 cyclic nucleotide binding domain containing 2
CNOT7 CCR4-NOT transcription complex, subunit 7
CPEB1 cytoplasmic polyadenylation element binding protein 1
CREM cAMP responsive element modulator
CRISP1 cysteine-rich secretory protein 1
CTSV cathepsin V
CUL4A cullin 4A
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25
DEDD death effector domain containing
DHH desert hedgehog
DMC1 DNA meiotic recombinase 1
DMRTC2 DMRT-like family C2
DND1 DND microRNA-mediated repression inhibitor 1
DPY19L2 dpy-19-like 2 (C. elegans)
EGR1 early growth response 1
EGR4 early growth response 4
EHD1 EH-domain containing 1
EHD4 EH-domain containing 4
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
ELOVL2 ELOVL fatty acid elongase 2
ENO4 enolase family member 4
EPB41L2 erythrocyte membrane protein band 4.1-like 2
ESR1 estrogen receptor 1
ETV5 ets variant 5
EXO1 exonuclease 1
FADS2 fatty acid desaturase 2
FANCA Fanconi anemia, complementation group A
FANCC Fanconi anemia, complementation group C
FANCG Fanconi anemia, complementation group G
FNDC3A fibronectin type III domain containing 3A
FSHB follicle stimulating hormone, beta polypeptide
FSHR follicle stimulating hormone receptor
FYN FYN proto-oncogene, Src family tyrosine kinase
GAL galanin/GMAP prepropeptide
GAL3ST1 galactose-3-O-sulfotransferase 1
GHR growth hormone receptor
GJA1 gap junction protein, alpha 1, 43kDa
GNRHR gonadotropin-releasing hormone receptor
GOLGA3 golgin A3
GPRC6A G protein-coupled receptor, class C, group 6, member A
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIP1 huntingtin interacting protein 1
HORMAD1 HORMA domain containing 1
HORMAD2 HORMA domain containing 2
HSF2 heat shock transcription factor 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA2 heat shock 70kDa protein 2
HSPA4 heat shock 70kDa protein 4
ING2 inhibitor of growth family, member 2
INHBA inhibin, beta A
JMJD1C jumonji domain containing 1C
KATNAL1 katanin p60 subunit A-like 1
KDM3A lysine (K)-specific demethylase 3A
KIF18A kinesin family member 18A
KISS1 KiSS-1 metastasis-suppressor
KISS1R KISS1 receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
LAMA2 laminin, alpha 2
LEP leptin
LHCGR luteinizing hormone/choriogonadotropin receptor
LIMK2 LIM domain kinase 2
LIPE lipase, hormone-sensitive
LOC101929327
M1AP meiosis 1 associated protein
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAP2 microtubule-associated protein 2
MARK2 MAP/microtubule affinity-regulating kinase 2
MCM8 minichromosome maintenance complex component 8
MEI4 meiosis-specific 4 homolog (S. cerevisiae)
MEIOB meiosis specific with OB domains
MNS1 meiosis-specific nuclear structural 1
MOV10L1 Mov10 RISC complex RNA helicase like 1
MSH4 mutS homolog 4
MSH5 mutS homolog 5
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NANOS2 nanos homolog 2 (Drosophila)
NANOS3 nanos homolog 3 (Drosophila)
NCOA2 nuclear receptor coactivator 2
NKX2-1 NK2 homeobox 1
NOS1 nitric oxide synthase 1 (neuronal)
NPHP1 nephronophthisis 1 (juvenile)
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR2C2 nuclear receptor subfamily 2, group C, member 2
NR5A1 nuclear receptor subfamily 5, group A, member 1
NXF2 nuclear RNA export factor 2
OTX2 orthodenticle homeobox 2
OVOL1 ovo-like zinc finger 1
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAPOLB poly(A) polymerase beta (testis specific)
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAX8 paired box 8
PCSK1 proprotein convertase subtilisin/kexin type 1
PHF13 PHD finger protein 13
PICK1 protein interacting with PRKCA 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIWIL1 piwi-like RNA-mediated gene silencing 1
PIWIL2 piwi-like RNA-mediated gene silencing 2
PIWIL4 piwi-like RNA-mediated gene silencing 4
PLK4 polo-like kinase 4
PRDM1 PR domain containing 1, with ZNF domain
PRDM9 PR domain containing 9
PRDX4 peroxiredoxin 4
PROKR2 prokineticin receptor 2
PSAP prosaposin
PTDSS2 phosphatidylserine synthase 2
PTH2 parathyroid hormone 2
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PTTG1 pituitary tumor-transforming 1
PUM1 pumilio RNA-binding family member 1
PUM2 pumilio RNA-binding family member 2
RABL2A RAB, member of RAS oncogene family-like 2A
RAD18 RAD18 E3 ubiquitin protein ligase
RAD51C RAD51 paralog C
ROR2 receptor tyrosine kinase-like orphan receptor 2
RXFP1 relaxin/insulin-like family peptide receptor 1
RXFP2 relaxin/insulin-like family peptide receptor 2
SAFB scaffold attachment factor B
SEPT12 septin 12
SH2B1 SH2B adaptor protein 1
SIRT1 sirtuin 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
SMC1B structural maintenance of chromosomes 1B
SNORD50A small nucleolar RNA, C/D box 50A
SNORD50B small nucleolar RNA, C/D box 50B
SNRPE small nuclear ribonucleoprotein polypeptide E
SOHLH1 spermatogenesis and oogenesis specific basic helix-loop-helix 1
SOX3 SRY (sex determining region Y)-box 3
SOX8 SRY (sex determining region Y)-box 8
SPATA22 spermatogenesis associated 22
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPO11 SPO11 meiotic protein covalently bound to DSB
STRBP spermatid perinuclear RNA binding protein
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
STX2 syntaxin 2
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SUN1 Sad1 and UNC84 domain containing 1
SYCE2 synaptonemal complex central element protein 2
SYCP1 synaptonemal complex protein 1
SYCP2 synaptonemal complex protein 2
SYCP3 synaptonemal complex protein 3
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
TASP1 taspase, threonine aspartase, 1
TBC1D20 TBC1 domain family, member 20
TBPL1 TBP-like 1
TCTE3 t-complex-associated-testis-expressed 3
TDRD5 tudor domain containing 5
TDRD9 tudor domain containing 9
TERT telomerase reverse transcriptase
TEX14 testis expressed 14
TEX15 testis expressed 15
THEG theg spermatid protein
TKT transketolase
TMF1 TATA element modulatory factor 1
TNF tumor necrosis factor
TP53 tumor protein p53
TPST2 tyrosylprotein sulfotransferase 2
UBE2B ubiquitin-conjugating enzyme E2B
UBE3A ubiquitin protein ligase E3A
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
VGF VGF nerve growth factor inducible
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
XPA xeroderma pigmentosum, complementation group A
ZC3HC1 zinc finger, C3HC-type containing 1
ZNF274 zinc finger protein 274
ZNF384 zinc finger protein 384