decreased t cell apoptosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description decrease in the number of T cells undergoing programmed cell death (Mammalian Phenotype Ontology, MP_0006414)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0006414
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Genes

30 gene mutations causing the decreased t cell apoptosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BMF Bcl2 modifying factor
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCDC86 coiled-coil domain containing 86
CD247 CD247 molecule
CD274 CD274 molecule
CDK6 cyclin-dependent kinase 6
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DTX1 deltex 1, E3 ubiquitin ligase
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
KLF13 Kruppel-like factor 13
LCN2 lipocalin 2
MAP2K3 mitogen-activated protein kinase kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
NDRG1 N-myc downstream regulated 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PERP PERP, TP53 apoptosis effector
PRF1 perforin 1 (pore forming protein)
PRKCQ protein kinase C, theta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RHOH ras homolog family member H
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
TMEM109 transmembrane protein 109
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TP53 tumor protein p53