decreased susceptibility to type iv hypersensitivity reaction Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less likelihood of or resistance to developing an antigen-elicited cellular immune reaction that results in tissue damage, but does not require Ab participation; the response is seen at the area of contact (Mammalian Phenotype Ontology, MP_0005616)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005616
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Genes

58 gene mutations causing the decreased susceptibility to type iv hypersensitivity reaction phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AHR aryl hydrocarbon receptor
ANXA5 annexin A5
APOE apolipoprotein E
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
CCL13 chemokine (C-C motif) ligand 13
CCL17 chemokine (C-C motif) ligand 17
CCL5 chemokine (C-C motif) ligand 5
CCR7 chemokine (C-C motif) receptor 7
CD207 CD207 molecule, langerin
CD28 CD28 molecule
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD83 CD83 molecule
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CLEC4D C-type lectin domain family 4, member D
CLEC4E C-type lectin domain family 4, member E
CXCL10 chemokine (C-X-C motif) ligand 10
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EPHB6 EPH receptor B6
F2RL1 coagulation factor II (thrombin) receptor-like 1
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
HLA-DMA major histocompatibility complex, class II, DM alpha
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IDO2 indoleamine 2,3-dioxygenase 2
IFNG interferon, gamma
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IGHM immunoglobulin heavy constant mu
IL12A interleukin 12A
IL12B interleukin 12B
IL15 interleukin 15
IL17A interleukin 17A
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL21R interleukin 21 receptor
IL3 interleukin 3
IL34 interleukin 34
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
MMP19 matrix metallopeptidase 19
MMP3 matrix metallopeptidase 3
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NPY1R neuropeptide Y receptor Y1
PGF placental growth factor
PTGDR2 prostaglandin D2 receptor 2
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PYCARD PYD and CARD domain containing
RAG2 recombination activating gene 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SPP1 secreted phosphoprotein 1
TNF tumor necrosis factor
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRIP10 thyroid hormone receptor interactor 10
TYROBP TYRO protein tyrosine kinase binding protein