decreased susceptibility to type ii hypersensitivity reaction Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less likelihood of or resistance to developing a response caused by an Ag-Ab reaction; antibodies are directly or indirectly cytotoxic to antigens on cell surfaces or in connective tissues; most often involves IgG and IgM; complement activation is usually involved (Mammalian Phenotype Ontology, MP_0005612)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005612
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Genes

2 gene mutations causing the decreased susceptibility to type ii hypersensitivity reaction phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CD40 CD40 molecule, TNF receptor superfamily member 5
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)