decreased susceptibility to neuronal excitotoxicity Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less than normal amount of neuronal cell death following exposure to a neurotoxic compound, such as kainate-induced neuronal cell death mediated via a glutamate excitotoxic process (Mammalian Phenotype Ontology, MP_0008236)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008236
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Genes

32 gene mutations causing the decreased susceptibility to neuronal excitotoxicity phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
BAG6 BCL2-associated athanogene 6
CASP12 caspase 12 (gene/pseudogene)
CASP6 caspase 6, apoptosis-related cysteine peptidase
CCL13 chemokine (C-C motif) ligand 13
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
FAF1 Fas (TNFRSF6) associated factor 1
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRM2 glutamate receptor, metabotropic 2
JUN jun proto-oncogene
MAOB monoamine oxidase B
MAPK10 mitogen-activated protein kinase 10
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MUTYH mutY homolog
NOS1 nitric oxide synthase 1 (neuronal)
PARP1 poly (ADP-ribose) polymerase 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLG plasminogen
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RASD1 RAS, dexamethasone-induced 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPP1 secreted phosphoprotein 1
SRR serine racemase
STAT1 signal transducer and activator of transcription 1, 91kDa
SURF1 surfeit 1
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TRPC5 transient receptor potential cation channel, subfamily C, member 5