decreased surfactant secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description decreased production or release from pneumocytes of surfactant, a phospholipid present in the lungs that controls surface tension in the alveoli (Mammalian Phenotype Ontology, MP_0010993)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010993
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Genes

7 gene mutations causing the decreased surfactant secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CTSH cathepsin H
FSTL1 follistatin-like 1
HOXA5 homeobox A5
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
NKX2-1 NK2 homeobox 1
PTHLH parathyroid hormone-like hormone