decreased spleen red pulp amount Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the quantity of the parenchymatous tissue network of the spleen that consists of loose plates or cords (sinuses) infiltrated with red blood cells where most of the blood filtration occurs and degenerate erythrocytes are removed from the circulation (Mammalian Phenotype Ontology, MP_0008477)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008477
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Genes

11 gene mutations causing the decreased spleen red pulp amount phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ASXL1 additional sex combs like transcriptional regulator 1
COL10A1 collagen, type X, alpha 1
DKC1 dyskeratosis congenita 1, dyskerin
GATA1 GATA binding protein 1 (globin transcription factor 1)
GGT1 gamma-glutamyltransferase 1
GSTK1 glutathione S-transferase kappa 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
LYN LYN proto-oncogene, Src family tyrosine kinase
SPI1 Spi-1 proto-oncogene
TP53 tumor protein p53