decreased serotonin level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the amount of biochemical messenger and regulator, found in the CNS, gastrointestinal tract, and produced by platelets that mediates neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity (Mammalian Phenotype Ontology, MP_0010070)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010070
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Genes

22 gene mutations causing the decreased serotonin level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
CELF6 CUGBP, Elav-like family member 6
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DISC1 disrupted in schizophrenia 1
DTNBP1 dystrobrevin binding protein 1
HPS1 Hermansky-Pudlak syndrome 1
HPS3 Hermansky-Pudlak syndrome 3
HPS4 Hermansky-Pudlak syndrome 4
HPS5 Hermansky-Pudlak syndrome 5
LYST lysosomal trafficking regulator
MAGED1 melanoma antigen family D1
MECP2 methyl CpG binding protein 2
RAB27A RAB27A, member RAS oncogene family
RAB27B RAB27B, member RAS oncogene family
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC35D3 solute carrier family 35, member D3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TPH2 tryptophan hydroxylase 2