decreased respiratory quotient Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism compared to controls (Mammalian Phenotype Ontology, MP_0010379)
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34 gene mutations causing the decreased respiratory quotient phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACACB acetyl-CoA carboxylase beta
ACOT13 acyl-CoA thioesterase 13
ADRB2 adrenoceptor beta 2, surface
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGRP agouti related neuropeptide
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPTL2 angiopoietin-like 2
BBS5 Bardet-Biedl syndrome 5
BSX brain-specific homeobox
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
FFAR4 free fatty acid receptor 4
FGL1 fibrinogen-like 1
FOXO1 forkhead box O1
FTO fat mass and obesity associated
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GPR12 G protein-coupled receptor 12
HADH hydroxyacyl-CoA dehydrogenase
INS insulin
KLF17 Kruppel-like factor 17
LEPR leptin receptor
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MCHR1 melanin-concentrating hormone receptor 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
PDE10A phosphodiesterase 10A
PDYN prodynorphin
PPP5C protein phosphatase 5, catalytic subunit
PRMT3 protein arginine methyltransferase 3
SIRT1 sirtuin 1
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TLR4 toll-like receptor 4
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)