decreased renal glomerular filtration rate Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less than the normal volume of water filtered out of the plasma through glomerular capillary walls into the Bowman's capsule per unit time (Mammalian Phenotype Ontology, MP_0005528)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005528
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Genes

11 gene mutations causing the decreased renal glomerular filtration rate phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
HNF1A HNF1 homeobox A
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
LGMN legumain
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRO protein tyrosine phosphatase, receptor type, O
REN renin
SGK1 serum/glucocorticoid regulated kinase 1
UMOD uromodulin
VEGFA vascular endothelial growth factor A