decreased prolactin level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less than expected concentration of the hormone that stimulates milk secretion (Mammalian Phenotype Ontology, MP_0005138)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005138
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Genes

19 gene mutations causing the decreased prolactin level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
CORT cortistatin
ESR1 estrogen receptor 1
GHRHR growth hormone releasing hormone receptor
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
INSM1 insulinoma-associated 1
IRS2 insulin receptor substrate 2
LATS1 large tumor suppressor kinase 1
LHX3 LIM homeobox 3
MARK2 MAP/microtubule affinity-regulating kinase 2
NPC1 Niemann-Pick disease, type C1
NPEPPS aminopeptidase puromycin sensitive
POU1F1 POU class 1 homeobox 1
PRL prolactin
PROP1 PROP paired-like homeobox 1
SOX2 SRY (sex determining region Y)-box 2
SST somatostatin
TRHR thyrotropin-releasing hormone receptor
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1