decreased platelet aggregation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009549
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Genes

48 gene mutations causing the decreased platelet aggregation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted
C6ORF25 chromosome 6 open reading frame 25
CAPN1 calpain 1, (mu/I) large subunit
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CLEC1B C-type lectin domain family 1, member B
CLIC1 chloride intracellular channel 1
DTNBP1 dystrobrevin binding protein 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
F2 coagulation factor II (thrombin)
FADS2 fatty acid desaturase 2
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FERMT3 fermitin family member 3
FGA fibrinogen alpha chain
FGG fibrinogen gamma chain
GAS6 growth arrest-specific 6
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
HPS3 Hermansky-Pudlak syndrome 3
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
LAT linker for activation of T cells
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
MERTK MER proto-oncogene, tyrosine kinase
NBEAL2 neurobeachin-like 2
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEK pleckstrin
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAB27A RAB27A, member RAS oncogene family
RAB27B RAB27B, member RAS oncogene family
RANBP10 RAN binding protein 10
RAP1B RAP1B, member of RAS oncogene family
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
STIM1 stromal interaction molecule 1
TBXAS1 thromboxane A synthase 1 (platelet)
TEC tec protein tyrosine kinase
TREML1 triggering receptor expressed on myeloid cells-like 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)