decreased plasma cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced number of terminally differentiated, post-mitotic, short-lived cells of the B cell lineage devoted to producing large amounts of immunoglobulin (Mammalian Phenotype Ontology, MP_0008098)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008098
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Genes

17 gene mutations causing the decreased plasma cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CD274 CD274 molecule
CD4 CD4 molecule
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GPR183 G protein-coupled receptor 183
ICOS inducible T-cell co-stimulator
IGHM immunoglobulin heavy constant mu
IL2RG interleukin 2 receptor, gamma
IRF4 interferon regulatory factor 4
JCHAIN joining chain of multimeric IgA and IgM
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NKX2-3 NK2 homeobox 3
PRDM1 PR domain containing 1, with ZNF domain
RGS1 regulator of G-protein signaling 1
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15