decreased pituitary hormone level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less than the expected amount of any of the pituitary hormones in the blood or tissues (Mammalian Phenotype Ontology, MP_0003972)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003972
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Genes

85 gene mutations causing the decreased pituitary hormone level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACVR2A activin A receptor, type IIA
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AMH anti-Mullerian hormone
AR androgen receptor
ASIP agouti signaling protein
AVPR1B arginine vasopressin receptor 1B
BRS3 bombesin-like receptor 3
CDK4 cyclin-dependent kinase 4
CGA glycoprotein hormones, alpha polypeptide
CLOCK clock circadian regulator
CORT cortistatin
CPE carboxypeptidase E
CRTC1 CREB regulated transcription coactivator 1
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DIO3 deiodinase, iodothyronine, type III
DRD2 dopamine receptor D2
EGR1 early growth response 1
ESR1 estrogen receptor 1
FGF21 fibroblast growth factor 21
FOXN1 forkhead box N1
FSHB follicle stimulating hormone, beta polypeptide
GHR growth hormone receptor
GHRH growth hormone releasing hormone
GHRHR growth hormone releasing hormone receptor
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRHR gonadotropin-releasing hormone receptor
HMX2 H6 family homeobox 2
HMX3 H6 family homeobox 3
IGF1 insulin-like growth factor 1 (somatomedin C)
INHA inhibin, alpha
INSM1 insulinoma-associated 1
IRS2 insulin receptor substrate 2
JUND jun D proto-oncogene
KISS1 KiSS-1 metastasis-suppressor
KISS1R KISS1 receptor
LATS1 large tumor suppressor kinase 1
LEPR leptin receptor
LHCGR luteinizing hormone/choriogonadotropin receptor
LHX3 LIM homeobox 3
LHX4 LIM homeobox 4
LIF leukemia inhibitory factor
LIN28A lin-28 homolog A (C. elegans)
MARK2 MAP/microtubule affinity-regulating kinase 2
MBD5 methyl-CpG binding domain protein 5
MBOAT4 membrane bound O-acyltransferase domain containing 4
MED1 mediator complex subunit 1
NHLH2 nescient helix loop helix 2
NOS1 nitric oxide synthase 1 (neuronal)
NPC1 Niemann-Pick disease, type C1
NPEPPS aminopeptidase puromycin sensitive
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUPR1 nuclear protein, transcriptional regulator, 1
OTX2 orthodenticle homeobox 2
PAX6 paired box 6
PCSK1 proprotein convertase subtilisin/kexin type 1
PCSK2 proprotein convertase subtilisin/kexin type 2
PDE8B phosphodiesterase 8B
PGR progesterone receptor
PITX2 paired-like homeodomain 2
POMC proopiomelanocortin
POU1F1 POU class 1 homeobox 1
PRL prolactin
PROKR2 prokineticin receptor 2
PROP1 PROP paired-like homeobox 1
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RIMS2 regulating synaptic membrane exocytosis 2
SERP1 stress-associated endoplasmic reticulum protein 1
SIRT1 sirtuin 1
SOCS2 suppressor of cytokine signaling 2
SOD1 superoxide dismutase 1, soluble
SOX2 SRY (sex determining region Y)-box 2
SOX3 SRY (sex determining region Y)-box 3
SST somatostatin
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TBX19 T-box 19
TRH thyrotropin-releasing hormone
TRHR thyrotropin-releasing hormone receptor
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1
VGF VGF nerve growth factor inducible
VIP vasoactive intestinal peptide