decreased peyer's patch number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the number of the protruding lymphoid tissue located on the mucosa of the small intestine that is composed of densely packed B cell follicles (Mammalian Phenotype Ontology, MP_0008133)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008133
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Genes

22 gene mutations causing the decreased peyer's patch number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BCL3 B-cell CLL/lymphoma 3
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CBFB core-binding factor, beta subunit
CCR6 chemokine (C-C motif) receptor 6
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL13 chemokine (C-X-C motif) ligand 13
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
GCSAM germinal center-associated, signaling and motility
GFRA1 GDNF family receptor alpha 1
IGHM immunoglobulin heavy constant mu
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NKX2-3 NK2 homeobox 3
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RUNX1 runt-related transcription factor 1
SASH3 SAM and SH3 domain containing 3
SPPL2A signal peptide peptidase like 2A
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TOX thymocyte selection-associated high mobility group box