decreased percent body fat Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less fat, relative to controls, as a percentage of total body weight (Mammalian Phenotype Ontology, MP_0005459)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005459
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Genes

78 gene mutations causing the decreased percent body fat phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADIPOR2 adiponectin receptor 2
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AKAP9 A kinase (PRKA) anchor protein 9
AKT1 v-akt murine thymoma viral oncogene homolog 1
APOE apolipoprotein E
ARID5B AT rich interactive domain 5B (MRF1-like)
ARRDC3 arrestin domain containing 3
ARSB arylsulfatase B
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
CD36 CD36 molecule (thrombospondin receptor)
CDH23 cadherin-related 23
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHD7 chromodomain helicase DNA binding protein 7
CLPS colipase, pancreatic
CNR1 cannabinoid receptor 1 (brain)
COL2A1 collagen, type II, alpha 1
CREBBP CREB binding protein
DBN1 drebrin 1
DDR2 discoidin domain receptor tyrosine kinase 2
DGAT1 diacylglycerol O-acyltransferase 1
DLG2 discs, large homolog 2 (Drosophila)
DLG4 discs, large homolog 4 (Drosophila)
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DUOX2 dual oxidase 2
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
ESRRA estrogen-related receptor alpha
FTO fat mass and obesity associated
GNAS GNAS complex locus
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GPR21 G protein-coupled receptor 21
GPR50 G protein-coupled receptor 50
GSK3A glycogen synthase kinase 3 alpha
HMGA2 high mobility group AT-hook 2
IDUA iduronidase, alpha-L-
IRS1 insulin receptor substrate 1
KAT6B K(lysine) acetyltransferase 6B
KLF3 Kruppel-like factor 3 (basic)
LMNA lamin A/C
MAPK8 mitogen-activated protein kinase 8
MARK2 MAP/microtubule affinity-regulating kinase 2
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MCHR1 melanin-concentrating hormone receptor 1
MOGAT2 monoacylglycerol O-acyltransferase 2
MSTN myostatin
MYO6 myosin VI
MYO7A myosin VIIA
MYSM1 Myb-like, SWIRM and MPN domains 1
NCOR1 nuclear receptor corepressor 1
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCNA proliferating cell nuclear antigen
PDE3B phosphodiesterase 3B, cGMP-inhibited
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PKNOX1 PBX/knotted 1 homeobox 1
PLIN1 perilipin 1
PNLIP pancreatic lipase
PNRC2 proline-rich nuclear receptor coactivator 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RBL1 retinoblastoma-like 1
RGN regucalcin
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC3 syndecan 3
SERTAD2 SERTA domain containing 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC25A30 solute carrier family 25, member 30
SLC30A7 solute carrier family 30 (zinc transporter), member 7
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TLR4 toll-like receptor 4
TMEM27 transmembrane protein 27
TNF tumor necrosis factor
UMOD uromodulin
USH1C Usher syndrome 1C (autosomal recessive, severe)
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble