decreased nk cell degranulation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the exocytosis of secretory granules containing preformed mediators, such as perforin and granzyme, from NK cells (Mammalian Phenotype Ontology, MP_0008791)
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5 gene mutations causing the decreased nk cell degranulation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
GFI1 growth factor independent 1 transcription repressor
PRF1 perforin 1 (pore forming protein)
RAB27A RAB27A, member RAS oncogene family
STAT1 signal transducer and activator of transcription 1, 91kDa
STX11 syntaxin 11