decreased neurotransmitter release Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced production or release of endogenous signaling molecules normally secreted by neurons that alter the behavior of neurons or effector cells (Mammalian Phenotype Ontology, MP_0003990)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003990
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Genes

20 gene mutations causing the decreased neurotransmitter release phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADGRL1 adhesion G protein-coupled receptor L1
AP3M2 adaptor-related protein complex 3, mu 2 subunit
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
DLG4 discs, large homolog 4 (Drosophila)
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
GDI1 GDP dissociation inhibitor 1
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS3 nitric oxide synthase 3 (endothelial cell)
NRXN1 neurexin 1
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SNAP25 synaptosomal-associated protein, 25kDa
SSTR1 somatostatin receptor 1
SYT2 synaptotagmin II
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UNC13A unc-13 homolog A (C. elegans)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)