decreased metastatic potential Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced likelihood of a tumor cell spreading from the site of the initial tumor formation and forming a secondary tumor at another site not directly connected with it (Mammalian Phenotype Ontology, MP_0001273)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001273
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Genes

23 gene mutations causing the decreased metastatic potential phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ANXA1 annexin A1
ATF3 activating transcription factor 3
CCM2L cerebral cavernous malformation 2-like
CXCR2 chemokine (C-X-C motif) receptor 2
CYBB cytochrome b-245, beta polypeptide
FBLN5 fibulin 5
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FOS FBJ murine osteosarcoma viral oncogene homolog
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
HCST hematopoietic cell signal transducer
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFNGR1 interferon gamma receptor 1
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
JAM3 junctional adhesion molecule 3
LYST lysosomal trafficking regulator
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MMP9 matrix metallopeptidase 9
PLAU plasminogen activator, urokinase
PLD1 phospholipase D1, phosphatidylcholine-specific
SELL selectin L
STAB2 stabilin 2
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced