decreased memory b cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced number of distinctly differentiated long-lived B cells that are readily activated upon reencounter of an antigenic determinant; memory B cells differentiate from antigen-activated B cells which have been selected for expression of higher affinity immunoglobulin (Mammalian Phenotype Ontology, MP_0008729)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008729
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Genes

2 gene mutations causing the decreased memory b cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CD22 CD22 molecule
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)