decreased macrophage cytokine production Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced production of macrophage-derived cytokine(s) due to biosynthesis or secretion following a cellular stimulus, resulting in an decrease in its intracellular or extracellular levels (Mammalian Phenotype Ontology, MP_0011079)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011079
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Genes

5 gene mutations causing the decreased macrophage cytokine production phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CCR6 chemokine (C-C motif) receptor 6
MCAM melanoma cell adhesion molecule
TICAM1 toll-like receptor adaptor molecule 1
TLR2 toll-like receptor 2
TNF tumor necrosis factor