decreased lymphocyte cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description fewer than normal number of the cells involved in adaptive immune reactions of the body in most inflammatory and autoimmune diseases, including B cells, T cells and natural killer cells (Mammalian Phenotype Ontology, MP_0005016)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005016
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Genes

617 gene mutations causing the decreased lymphocyte cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACKR3 atypical chemokine receptor 3
ACP2 acid phosphatase 2, lysosomal
ACSL3 acyl-CoA synthetase long-chain family member 3
ADA adenosine deaminase
ADGRF5 adhesion G protein-coupled receptor F5
AFF1 AF4/FMR2 family, member 1
AIM2 absent in melanoma 2
AIRE autoimmune regulator
AKAP13 A kinase (PRKA) anchor protein 13
AKAP9 A kinase (PRKA) anchor protein 9
AMPD3 adenosine monophosphate deaminase 3
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
APC adenomatous polyposis coli
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
APOE apolipoprotein E
ARHGAP15 Rho GTPase activating protein 15
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARID4A AT rich interactive domain 4A (RBP1-like)
ARID5A AT rich interactive domain 5A (MRF1-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL4D ADP-ribosylation factor-like 4D
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASL argininosuccinate lyase
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASXL1 additional sex combs like transcriptional regulator 1
ATF2 activating transcription factor 2
ATG16L2 autophagy related 16-like 2 (S. cerevisiae)
ATM ATM serine/threonine kinase
ATP11C ATPase, class VI, type 11C
B2M beta-2-microglobulin
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
B9D1 B9 protein domain 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAD BCL2-associated agonist of cell death
BAG3 BCL2-associated athanogene 3
BATF basic leucine zipper transcription factor, ATF-like
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCL10 B-cell CLL/lymphoma 10
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BCL6B B-cell CLL/lymphoma 6, member B
BCLAF1 BCL2-associated transcription factor 1
BHLHE40 basic helix-loop-helix family, member e40
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BLNK B-cell linker
BMF Bcl2 modifying factor
BRAF B-Raf proto-oncogene, serine/threonine kinase
BST1 bone marrow stromal cell antigen 1
BTK Bruton agammaglobulinemia tyrosine kinase
C10ORF11 chromosome 10 open reading frame 11
C17ORF62 chromosome 17 open reading frame 62
C3AR1 complement component 3a receptor 1
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CACYBP calcyclin binding protein
CADM1 cell adhesion molecule 1
CARD11 caspase recruitment domain family, member 11
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBFB core-binding factor, beta subunit
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC171 coiled-coil domain containing 171
CCL13 chemokine (C-C motif) ligand 13
CCL19 chemokine (C-C motif) ligand 19
CCL25 chemokine (C-C motif) ligand 25
CCL5 chemokine (C-C motif) ligand 5
CCND3 cyclin D3
CCR1 chemokine (C-C motif) receptor 1
CCR10 chemokine (C-C motif) receptor 10
CCR2 chemokine (C-C motif) receptor 2
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CCR9 chemokine (C-C motif) receptor 9
CD19 CD19 molecule
CD1D CD1d molecule
CD22 CD22 molecule
CD247 CD247 molecule
CD27 CD27 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD47 CD47 molecule
CD5 CD5 molecule
CD5L CD5 molecule-like
CD69 CD69 molecule
CD70 CD70 molecule
CD72 CD72 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CD81 CD81 molecule
CD83 CD83 molecule
CD84 CD84 molecule
CD86 CD86 molecule
CD8A CD8a molecule
CD8B CD8b molecule
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDK6 cyclin-dependent kinase 6
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CHD2 chromodomain helicase DNA binding protein 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CIITA class II, major histocompatibility complex, transactivator
CLEC10A C-type lectin domain family 10, member A
CLEC4E C-type lectin domain family 4, member E
CLK1 CDC-like kinase 1
COL10A1 collagen, type X, alpha 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
CORO1A coronin, actin binding protein, 1A
CR2 complement component (3d/Epstein Barr virus) receptor 2
CREBBP CREB binding protein
CRIP3 cysteine-rich protein 3
CRLF2 cytokine receptor-like factor 2
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CTCF CCCTC-binding factor (zinc finger protein)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSD cathepsin D
CTSV cathepsin V
CUX1 cut-like homeobox 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL16 chemokine (C-X-C motif) ligand 16
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYCS cytochrome c, somatic
CYLD cylindromatosis (turban tumor syndrome)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYTIP cytohesin 1 interacting protein
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCBLD2 discoidin, CUB and LCCL domain containing 2
DCK deoxycytidine kinase
DCLRE1C DNA cross-link repair 1C
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DGKZ diacylglycerol kinase, zeta
DIAPH1 diaphanous-related formin 1
DKC1 dyskeratosis congenita 1, dyskerin
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
DLL1 delta-like 1 (Drosophila)
DMTF1 cyclin D binding myb-like transcription factor 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DNTT DNA nucleotidylexotransferase
DOCK2 dedicator of cytokinesis 2
DOCK8 dedicator of cytokinesis 8
DTX1 deltex 1, E3 ubiquitin ligase
E2F1 E2F transcription factor 1
E2F4 E2F transcription factor 4, p107/p130-binding
EBF1 early B-cell factor 1
EBI3 Epstein-Barr virus induced 3
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ELF4 E74-like factor 4 (ets domain transcription factor)
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ELMOD1 ELMO/CED-12 domain containing 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EOMES eomesodermin
EP300 E1A binding protein p300
EPS15 epidermal growth factor receptor pathway substrate 15
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EWSR1 EWS RNA-binding protein 1
F3 coagulation factor III (thromboplastin, tissue factor)
FADS1 fatty acid desaturase 1
FAM104A family with sequence similarity 104, member A
FAM63A family with sequence similarity 63, member A
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBXO7 F-box protein 7
FCMR Fc fragment of IgM receptor
FES FES proto-oncogene, tyrosine kinase
FGF23 fibroblast growth factor 23
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
FNIP1 folliculin interacting protein 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXN1 forkhead box N1
FOXP1 forkhead box P1
FOXP3 forkhead box P3
FUS FUS RNA binding protein
FYB FYN binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
FZD9 frizzled class receptor 9
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GADD45A growth arrest and DNA-damage-inducible, alpha
GALC galactosylceramidase
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GALR2 galanin receptor 2
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA3 GATA binding protein 3
GCLC glutamate-cysteine ligase, catalytic subunit
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GFI1 growth factor independent 1 transcription repressor
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
GIMAP6 GTPase, IMAP family member 6
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GON4L gon-4-like (C. elegans)
GPER1 G protein-coupled estrogen receptor 1
GPR15 G protein-coupled receptor 15
GPR183 G protein-coupled receptor 183
GPR83 G protein-coupled receptor 83
GRAP2 GRB2-related adaptor protein 2
GSE1 Gse1 coiled-coil protein
GSX1 GS homeobox 1
H2AFX H2A histone family, member X
HAX1 HCLS1 associated protein X-1
HBP1 HMG-box transcription factor 1
HCLS1 hematopoietic cell-specific Lyn substrate 1
HCST hematopoietic cell signal transducer
HELLS helicase, lymphoid-specific
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-A major histocompatibility complex, class I, A
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-G major histocompatibility complex, class I, G
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like
HPRT1 hypoxanthine phosphoribosyltransferase 1
HR hair growth associated
HRH1 histamine receptor H1
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTRA2 HtrA serine peptidase 2
ICOS inducible T-cell co-stimulator
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IER3 immediate early response 3
IFITM1 interferon induced transmembrane protein 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNB1 interferon, beta 1, fibroblast
IFNE interferon, epsilon
IFNGR1 interferon gamma receptor 1
IGHD immunoglobulin heavy constant delta
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGLC1 immunoglobulin lambda constant 1 (Mcg marker)
IGLL1 immunoglobulin lambda-like polypeptide 1
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL13 interleukin 13
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL17A interleukin 17A
IL17C interleukin 17C
IL17F interleukin 17F
IL17RB interleukin 17 receptor B
IL1R1 interleukin 1 receptor, type I
IL1RL2 interleukin 1 receptor-like 2
IL2 interleukin 2
IL21 interleukin 21
IL21R interleukin 21 receptor
IL23A interleukin 23, alpha subunit p19
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL33 interleukin 33
IL4R interleukin 4 receptor
IL5RA interleukin 5 receptor, alpha
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
IL7 interleukin 7
IL7R interleukin 7 receptor
ING1 inhibitor of growth family, member 1
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
IRF4 interferon regulatory factor 4
IRF8 interferon regulatory factor 8
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA6 integrin, alpha 6
ITGAD integrin, alpha D
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB7 integrin, beta 7
ITK IL2-inducible T-cell kinase
ITPKB inositol-trisphosphate 3-kinase B
JAG2 jagged 2
JAK1 Janus kinase 1
JAK3 Janus kinase 3
JCHAIN joining chain of multimeric IgA and IgM
KAT6A K(lysine) acetyltransferase 6A
KAZN kazrin, periplakin interacting protein
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KDM4C lysine (K)-specific demethylase 4C
KIAA1549L KIAA1549-like
KIFAP3 kinesin-associated protein 3
KISS1R KISS1 receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KL klotho
KLF13 Kruppel-like factor 13
KLHDC2 kelch domain containing 2
KLHL6 kelch-like family member 6
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2A lysine (K)-specific methyltransferase 2A
KMT2E lysine (K)-specific methyltransferase 2E
KPTN kaptin (actin binding protein)
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAMA2 laminin, alpha 2
LAT linker for activation of T cells
LBR lamin B receptor
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LEP leptin
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS9B lectin, galactoside-binding, soluble, 9B
LIG4 ligase IV, DNA, ATP-dependent
LRFN2 leucine rich repeat and fibronectin type III domain containing 2
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYN LYN proto-oncogene, Src family tyrosine kinase
LYST lysosomal trafficking regulator
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MALT1 MALT1 paracaspase
MAML1 mastermind-like 1 (Drosophila)
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAPK3 mitogen-activated protein kinase 3
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
MAVS mitochondrial antiviral signaling protein
MCF2L MCF.2 cell line derived transforming sequence-like
MCL1 myeloid cell leukemia 1
MCM4 minichromosome maintenance complex component 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEFV Mediterranean fever
MERTK MER proto-oncogene, tyrosine kinase
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MIR150 microRNA 150
MIR155 microRNA 155
MIR210 microRNA 210
MMP12 matrix metallopeptidase 12
MMP19 matrix metallopeptidase 19
MPZL2 myelin protein zero-like 2
MRAS muscle RAS oncogene homolog
MRC1 mannose receptor, C type 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSH2 mutS homolog 2
MSI2 musashi RNA-binding protein 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTSS1 metastasis suppressor 1
MYB v-myb avian myeloblastosis viral oncogene homolog
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYO1G myosin IG
MYSM1 Myb-like, SWIRM and MPN domains 1
MYT1L myelin transcription factor 1-like
NBN nibrin
NCAPH2 non-SMC condensin II complex, subunit H2
NCKAP1L NCK-associated protein 1-like
NCR1 natural cytotoxicity triggering receptor 1
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NF1 neurofibromin 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
NFE2L2 nuclear factor, erythroid 2-like 2
NFIL3 nuclear factor, interleukin 3 regulated
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NHEJ1 nonhomologous end-joining factor 1
NIPAL3 NIPA-like domain containing 3
NKX2-3 NK2 homeobox 3
NLK nemo-like kinase
NLRC5 NLR family, CARD domain containing 5
NLRP3 NLR family, pyrin domain containing 3
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NPC2 Niemann-Pick disease, type C2
NPY1R neuropeptide Y receptor Y1
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUP98 nucleoporin 98kDa
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PARL presenilin associated, rhomboid-like
PARP14 poly (ADP-ribose) polymerase family, member 14
PARVB parvin, beta
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAX1 paired box 1
PAX5 paired box 5
PBX1 pre-B-cell leukemia homeobox 1
PCGF2 polycomb group ring finger 2
PCSK1 proprotein convertase subtilisin/kexin type 1
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PFDN1 prefoldin subunit 1
PGM3 phosphoglucomutase 3
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKNOX1 PBX/knotted 1 homeobox 1
PLA2G10 phospholipase A2, group X
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLCL2 phospholipase C-like 2
PNP purine nucleoside phosphorylase
POLM polymerase (DNA directed), mu
POU1F1 POU class 1 homeobox 1
POU2AF1 POU class 2 associating factor 1
POU2F2 POU class 2 homeobox 2
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PRDM1 PR domain containing 1, with ZNF domain
PRKCB protein kinase C, beta
PRKCH protein kinase C, eta
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRSS50 protease, serine, 50
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PTCRA pre T-cell antigen receptor alpha
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PYCARD PYD and CARD domain containing
RAD50 RAD50 homolog (S. cerevisiae)
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RASA3 RAS p21 protein activator 3
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RBBP7 retinoblastoma binding protein 7
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RGS1 regulator of G-protein signaling 1
RGS13 regulator of G-protein signaling 13
RGS5 regulator of G-protein signaling 5
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOH ras homolog family member H
RIC1 RAB6A GEF complex partner 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
RNASE10 ribonuclease, RNase A family, 10 (non-active)
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RORC RAR-related orphan receptor C
RPL22 ribosomal protein L22
RRAS related RAS viral (r-ras) oncogene homolog
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
RUVBL2 RuvB-like AAA ATPase 2
S1PR1 sphingosine-1-phosphate receptor 1
S1PR5 sphingosine-1-phosphate receptor 5
SAP130 Sin3A-associated protein, 130kDa
SASH3 SAM and SH3 domain containing 3
SATB1 SATB homeobox 1
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SELL selectin L
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SEPT8 septin 8
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SETMAR SET domain and mariner transposase fusion gene
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SGMS1 sphingomyelin synthase 1
SGOL1 shugoshin-like 1 (S. pombe)
SGPL1 sphingosine-1-phosphate lyase 1
SH2B3 SH2B adaptor protein 3
SH2D1A SH2 domain containing 1A
SH2D3C SH2 domain containing 3C
SH3BP2 SH3-domain binding protein 2
SHARPIN SHANK-associated RH domain interactor
SHCBP1 SHC SH2-domain binding protein 1
SIAE sialic acid acetylesterase
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIRPA signal-regulatory protein alpha
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SIRT6 sirtuin 6
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC39A3 solute carrier family 39 (zinc transporter), member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SOCS1 suppressor of cytokine signaling 1
SORBS1 sorbin and SH3 domain containing 1
SOX13 SRY (sex determining region Y)-box 13
SOX4 SRY (sex determining region Y)-box 4
SP3 Sp3 transcription factor
SPI1 Spi-1 proto-oncogene
SPNS2 spinster homolog 2 (Drosophila)
SPPL2A signal peptide peptidase like 2A
SSBP2 single-stranded DNA binding protein 2
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK17B serine/threonine kinase 17b
STK4 serine/threonine kinase 4
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
SYK spleen tyrosine kinase
SYTL1 synaptotagmin-like 1
TACC3 transforming, acidic coiled-coil containing protein 3
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TBK1 TANK-binding kinase 1
TBX21 T-box 21
TCF12 transcription factor 12
TCF3 transcription factor 3
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TDP2 tyrosyl-DNA phosphodiesterase 2
TESPA1 thymocyte expressed, positive selection associated 1
TET2 tet methylcytosine dioxygenase 2
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
THEMIS thymocyte selection associated
TICAM1 toll-like receptor adaptor molecule 1
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TMC6 transmembrane channel-like 6
TMEM127 transmembrane protein 127
TMEM189 transmembrane protein 189
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TOX thymocyte selection-associated high mobility group box
TP53BP1 tumor protein p53 binding protein 1
TPP2 tripeptidyl peptidase II
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRBV14 T cell receptor beta variable 14
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIB2 tribbles pseudokinase 2
TSHR thyroid stimulating hormone receptor
TUSC2 tumor suppressor candidate 2
TWSG1 twisted gastrulation BMP signaling modulator 1
TXNIP thioredoxin interacting protein
UNC93B1 unc-93 homolog B1 (C. elegans)
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VPREB1 pre-B lymphocyte 1
WAS Wiskott-Aldrich syndrome
WDR37 WD repeat domain 37
WIPF1 WAS/WASL interacting protein family, member 1
WNT1 wingless-type MMTV integration site family, member 1
WNT4 wingless-type MMTV integration site family, member 4
WTAP Wilms tumor 1 associated protein
XCL1 chemokine (C motif) ligand 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB1 zinc finger and BTB domain containing 1
ZBTB16 zinc finger and BTB domain containing 16
ZBTB7A zinc finger and BTB domain containing 7A
ZBTB7B zinc finger and BTB domain containing 7B
ZC3HC1 zinc finger, C3HC-type containing 1
ZEB1 zinc finger E-box binding homeobox 1
ZFP36 ZFP36 ring finger protein
ZNF175 zinc finger protein 175
ZNF335 zinc finger protein 335