decreased interleukin-5 secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the production or release of a cytokine that promotes differentiation and activation of eosinophils; it also triggers activated B-cells to differentiate into immunoglobulin-secreting cells (Mammalian Phenotype Ontology, MP_0008703)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008703
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Genes

22 gene mutations causing the decreased interleukin-5 secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BHLHE41 basic helix-loop-helix family, member e41
CCL13 chemokine (C-C motif) ligand 13
CCR4 chemokine (C-C motif) receptor 4
CCR6 chemokine (C-C motif) receptor 6
CCRL2 chemokine (C-C motif) receptor-like 2
FPR2 formyl peptide receptor 2
HRH1 histamine receptor H1
ICOS inducible T-cell co-stimulator
IL13 interleukin 13
IL17RB interleukin 17 receptor B
IL1RL1 interleukin 1 receptor-like 1
IL25 interleukin 25
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
PRKCQ protein kinase C, theta
RAD50 RAD50 homolog (S. cerevisiae)
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RSAD2 radical S-adenosyl methionine domain containing 2
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11