decreased interleukin-18 secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the production or release of a cytokine which enhances the cytotoxic activity of NK cells and cytotoxic T-cells and appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity (Mammalian Phenotype Ontology, MP_0008685)
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4 gene mutations causing the decreased interleukin-18 secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AIM2 absent in melanoma 2
GBP5 guanylate binding protein 5
NLRP6 NLR family, pyrin domain containing 6
PYCARD PYD and CARD domain containing