decreased interleukin-17 secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the production or release of a proinflammatory cytokine produced primarily by T-cells or their precursors (Mammalian Phenotype Ontology, MP_0008682)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008682
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Genes

22 gene mutations causing the decreased interleukin-17 secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BATF basic leucine zipper transcription factor, ATF-like
CD274 CD274 molecule
CLEC6A C-type lectin domain family 6, member A
CRTAM cytotoxic and regulatory T cell molecule
IL12B interleukin 12B
IL17A interleukin 17A
IL17C interleukin 17C
IL17F interleukin 17F
IL17RA interleukin 17 receptor A
IL17RB interleukin 17 receptor B
IL1RL2 interleukin 1 receptor-like 2
IL21R interleukin 21 receptor
IL23A interleukin 23, alpha subunit p19
IL6 interleukin 6
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
NFIL3 nuclear factor, interleukin 3 regulated
NLRP10 NLR family, pyrin domain containing 10
PRKCQ protein kinase C, theta
RFTN1 raftlin, lipid raft linker 1
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13