decreased igg3 level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less than normal immunoglobulin class G3 level (Mammalian Phenotype Ontology, MP_0008498)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008498
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Genes

72 gene mutations causing the decreased igg3 level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AICDA activation-induced cytidine deaminase
ATM ATM serine/threonine kinase
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BLNK B-cell linker
BST1 bone marrow stromal cell antigen 1
BTK Bruton agammaglobulinemia tyrosine kinase
CARD11 caspase recruitment domain family, member 11
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CD180 CD180 molecule
CD19 CD19 molecule
CD22 CD22 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD79A CD79a molecule, immunoglobulin-associated alpha
CD83 CD83 molecule
CR2 complement component (3d/Epstein Barr virus) receptor 2
CYLD cylindromatosis (turban tumor syndrome)
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DLL1 delta-like 1 (Drosophila)
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FLI1 Fli-1 proto-oncogene, ETS transcription factor
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
HOXC4 homeobox C4
HRH1 histamine receptor H1
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IGHM immunoglobulin heavy constant mu
IGLL1 immunoglobulin lambda-like polypeptide 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL21R interleukin 21 receptor
IL2RG interleukin 2 receptor, gamma
IL5RA interleukin 5 receptor, alpha
ITFG2 integrin alpha FG-GAP repeat containing 2
LIG4 ligase IV, DNA, ATP-dependent
LTA lymphotoxin alpha
LY86 lymphocyte antigen 86
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MARK2 MAP/microtubule affinity-regulating kinase 2
MSH2 mutS homolog 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYD88 myeloid differentiation primary response 88
MYO6 myosin VI
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NHEJ1 nonhomologous end-joining factor 1
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PITX3 paired-like homeodomain 3
POU2AF1 POU class 2 associating factor 1
PRKCB protein kinase C, beta
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RIF1 replication timing regulatory factor 1
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
SH2D1A SH2 domain containing 1A
SH2D3C SH2 domain containing 3C
SH3BP2 SH3-domain binding protein 2
SPPL2A signal peptide peptidase like 2A
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TNF tumor necrosis factor
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
UNG uracil-DNA glycosylase
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor