decreased igg2b level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less than normal immunoglobulin class G2b level (Mammalian Phenotype Ontology, MP_0008497)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008497
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Genes

59 gene mutations causing the decreased igg2b level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AICDA activation-induced cytidine deaminase
ATM ATM serine/threonine kinase
AVPR1A arginine vasopressin receptor 1A
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
CARD11 caspase recruitment domain family, member 11
CD180 CD180 molecule
CD19 CD19 molecule
CD28 CD28 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD79A CD79a molecule, immunoglobulin-associated alpha
CD83 CD83 molecule
CR2 complement component (3d/Epstein Barr virus) receptor 2
DLL1 delta-like 1 (Drosophila)
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FPR2 formyl peptide receptor 2
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
HOXC4 homeobox C4
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
IFNG interferon, gamma
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGLL1 immunoglobulin lambda-like polypeptide 1
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL17A interleukin 17A
IL21R interleukin 21 receptor
IL6ST interleukin 6 signal transducer
IRF1 interferon regulatory factor 1
ITFG2 integrin alpha FG-GAP repeat containing 2
ITPKB inositol-trisphosphate 3-kinase B
LIG4 ligase IV, DNA, ATP-dependent
LY86 lymphocyte antigen 86
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MYD88 myeloid differentiation primary response 88
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
POU2AF1 POU class 2 associating factor 1
PVR poliovirus receptor
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RIF1 replication timing regulatory factor 1
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
SH2D1A SH2 domain containing 1A
SH2D3C SH2 domain containing 3C
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPPL2A signal peptide peptidase like 2A
SYK spleen tyrosine kinase
SYTL1 synaptotagmin-like 1
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
VAV2 vav 2 guanine nucleotide exchange factor