decreased ige level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less than normal immunoglobulin class E level (Mammalian Phenotype Ontology, MP_0002492)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002492
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Genes

55 gene mutations causing the decreased ige level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BATF basic leucine zipper transcription factor, ATF-like
C3AR1 complement component 3a receptor 1
CARD11 caspase recruitment domain family, member 11
CCR4 chemokine (C-C motif) receptor 4
CCR6 chemokine (C-C motif) receptor 6
CD19 CD19 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
ECM1 extracellular matrix protein 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FNIP1 folliculin interacting protein 1
FPR2 formyl peptide receptor 2
FYN FYN proto-oncogene, Src family tyrosine kinase
HMGN5 high mobility group nucleosome binding domain 5
HOXC4 homeobox C4
HRH4 histamine receptor H4
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
IFNG interferon, gamma
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IL13 interleukin 13
IL13RA1 interleukin 13 receptor, alpha 1
IL17A interleukin 17A
IL17RB interleukin 17 receptor B
IL1RL1 interleukin 1 receptor-like 1
IL21R interleukin 21 receptor
IL2RG interleukin 2 receptor, gamma
IL33 interleukin 33
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL6 interleukin 6
ITFG2 integrin alpha FG-GAP repeat containing 2
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LTB4R leukotriene B4 receptor
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MMP9 matrix metallopeptidase 9
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFIL3 nuclear factor, interleukin 3 regulated
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
PLA2G10 phospholipase A2, group X
POU2AF1 POU class 2 associating factor 1
PTGDR2 prostaglandin D2 receptor 2
REL v-rel avian reticuloendotheliosis viral oncogene homolog
SH2D1A SH2 domain containing 1A
SHARPIN SHANK-associated RH domain interactor
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SWAP70 SWAP switching B-cell complex 70kDa subunit
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRIP10 thyroid hormone receptor interactor 10
VIPR2 vasoactive intestinal peptide receptor 2