decreased iga level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less than normal immunoglobulin class A level (Mammalian Phenotype Ontology, MP_0001807)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001807
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Genes

50 gene mutations causing the decreased iga level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AICDA activation-induced cytidine deaminase
ATP11C ATPase, class VI, type 11C
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BATF basic leucine zipper transcription factor, ATF-like
BST1 bone marrow stromal cell antigen 1
CARD11 caspase recruitment domain family, member 11
CCR10 chemokine (C-C motif) receptor 10
CCR6 chemokine (C-C motif) receptor 6
CD19 CD19 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD79B CD79b molecule, immunoglobulin-associated beta
CD83 CD83 molecule
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DLL1 delta-like 1 (Drosophila)
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
HOXC4 homeobox C4
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
IFNG interferon, gamma
IGHM immunoglobulin heavy constant mu
IL21R interleukin 21 receptor
IL23A interleukin 23, alpha subunit p19
IL5RA interleukin 5 receptor, alpha
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
LIG4 ligase IV, DNA, ATP-dependent
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MYSM1 Myb-like, SWIRM and MPN domains 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PARP14 poly (ADP-ribose) polymerase family, member 14
PIGR polymeric immunoglobulin receptor
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
POU2AF1 POU class 2 associating factor 1
PVR poliovirus receptor
RAG2 recombination activating gene 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RIF1 replication timing regulatory factor 1
SH3BP2 SH3-domain binding protein 2
SHARPIN SHANK-associated RH domain interactor
SPPL2A signal peptide peptidase like 2A
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TNF tumor necrosis factor
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13