decreased hippocampal commissure size Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced size of the triangular subcallosal plate of commissural fibers resulting from the converging of the right and left fornix bundles which exchange numerous fibers and which curve back in the contralateral fornix to end in the hippocampus of the opposite side (Mammalian Phenotype Ontology, MP_0008222)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008222
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Genes

5 gene mutations causing the decreased hippocampal commissure size phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APP amyloid beta (A4) precursor protein
CABLES1 Cdk5 and Abl enzyme substrate 1
DRAXIN dorsal inhibitory axon guidance protein
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)