decreased hepatocyte proliferation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduction in the expansion rate of the hepatocyte cell population by cell division (Mammalian Phenotype Ontology, MP_0004001)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004001
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Genes

21 gene mutations causing the decreased hepatocyte proliferation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
C3 complement component 3
CAV1 caveolin 1, caveolae protein, 22kDa
CCNDBP1 cyclin D-type binding-protein 1
CDK2 cyclin-dependent kinase 2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
ERCC1 excision repair cross-complementation group 1
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
IL6R interleukin 6 receptor
JUN jun proto-oncogene
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
NFE2L2 nuclear factor, erythroid 2-like 2
NR1I2 nuclear receptor subfamily 1, group I, member 2
PROX1 prospero homeobox 1
REG1B regenerating islet-derived 1 beta
RXRA retinoid X receptor, alpha
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SPTBN1 spectrin, beta, non-erythrocytic 1
XBP1 X-box binding protein 1